Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.58 |
| ▸ | AHR | P35869 | 1/20 | 0.45 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.38 |
| ▸ | CBLB | Q13191 | 8/20 | 0.38 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 5/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | PGK1 | P00558 | 1/20 | 0.35 |
| ▸ | PGK2 | P07205 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22493452 | 0.80 | P2RX7 (0.61) | P2RX7AHRDDR1CBLBTAS2R14 | |
| SCHEMBL31126771 | 0.80 | P2RX7 (0.61) | P2RX7AHRDDR1CBLBTAS2R14 | |
| Bromide SCHEMBL31126732 | 0.79 | P2RX7 (0.59) | P2RX7AHRDDR1CBLBTAS2R14 | |
| SCHEMBL27737055 | 0.79 | P2RX7 (0.68) | P2RX7AHRDDR1CBLBTAS2R14 | |
| SCHEMBL24443459 | 0.76 | P2RX7 (0.60) | P2RX7AHRDDR1CBLBTAS2R14 | |
| SCHEMBL29777642 | 0.76 | P2RX7 (0.60) | P2RX7AHRDDR1CBLBTAS2R14 | |
| SCHEMBL496206 | 0.75 | P2RX7 (0.64) | P2RX7AHRTAS2R14IRAK4PGK1 | |
| SCHEMBL28015459 | 0.75 | P2RX7 (0.64) | P2RX7AHRDDR1CBLBTAS2R14 | |
| SCHEMBL29375278 | 0.75 | P2RX7 (0.64) | P2RX7AHRTAS2R14IRAK4PGK1 | |
| Formic Acid SCHEMBL30892563 | 0.75 | P2RX7 (0.59) | P2RX7AHRTAS2R14IRAK4PGK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023097230-A1 | SPIROCYCLIC BICYCLIC MODULATORS OF CHOLESTEROL BIOSYNTHESIS AND THEIR USE FOR PROMOTING REMYELINATION | GENENTECH, INC. (US) | 2023-06-01 | — | — | WO | disclosed |