Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.64 |
| ▸ | AHR | P35869 | 1/20 | 0.51 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.43 |
| ▸ | PGK1 | P00558 | 1/20 | 0.41 |
| ▸ | PGK2 | P07205 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CBLB | Q13191 | 5/20 | 0.37 |
| ▸ | IDH1 | O75874 | 1/20 | 0.37 |
| ▸ | IDH2 | P48735 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27737055 | 0.88 | P2RX7 (0.68) | P2RX7AHRTAS2R14PGK1PGK2 | |
| SCHEMBL496206 | 0.84 | P2RX7 (0.64) | P2RX7AHRTAS2R14PGK1PGK2 | |
| SCHEMBL29375278 | 0.84 | P2RX7 (0.64) | P2RX7AHRTAS2R14PGK1PGK2 | |
| SCHEMBL13388397 | 0.82 | P2RX7 (0.62) | P2RX7AHRTAS2R14PGK1PGK2 | |
| SCHEMBL2826285 | 0.82 | P2RX7 (0.67) | P2RX7AHRTAS2R14PGK1PGK2 | |
| SCHEMBL29799817 | 0.82 | P2RX7 (0.62) | P2RX7AHRTAS2R14PGK1PGK2 | |
| SCHEMBL29709918 | 0.82 | P2RX7 (0.62) | P2RX7AHRTAS2R14PGK1PGK2 | |
| SCHEMBL13043982 | 0.82 | P2RX7 (0.62) | P2RX7AHRTAS2R14PGK1PGK2 | |
| SCHEMBL22832289 | 0.80 | KDM4E (0.59) | P2RX7KDM4EALOX15TSHRACMSD | |
| SCHEMBL24198761 | 0.79 | P2RX7 (0.58) | P2RX7AHRTAS2R14PGK1PGK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104640844-B | The preparation method of 4-amino-5-fluorine-3-halo-6-(substituted) pyridine-2-formic acid esters | 美国陶氏益农公司 | 2016-11-09 | — | — | CN | disclosed |
| CN-104640844-A | Process for the preparation of 4-amino-5-fluoro-3-halo-6-(substituted)picolinates-2-formate | DOW AGROSCIENCES LLC | 2015-05-20 | — | — | CN | disclosed |