Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | AHR | P35869 | 1/20 | 0.51 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GNE | Q9Y223 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | PGK1 | P00558 | 1/20 | 0.41 |
| ▸ | PGK2 | P07205 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29375278 | 1.00 | P2RX7 (0.64) | P2RX7KDM4EALOX15TSHRACMSD | |
| Methylene Chloride SCHEMBL28293379 | 0.93 | P2RX7 (0.61) | P2RX7KDM4EALOX15TSHRACMSD | |
| SCHEMBL27737055 | 0.88 | P2RX7 (0.68) | P2RX7KDM4EALOX15TSHRACMSD | |
| SCHEMBL22835203 | 0.85 | KDM4E (0.57) | P2RX7KDM4EALOX15TSHRACMSD | |
| SCHEMBL19029854 | 0.85 | KDM4E (0.57) | P2RX7KDM4EALOX15TSHRACMSD | |
| SCHEMBL14354517 | 0.85 | KDM4E (0.57) | P2RX7KDM4EALOX15TSHRACMSD | |
| SCHEMBL29381032 | 0.85 | KDM4E (0.57) | P2RX7KDM4EALOX15TSHRACMSD | |
| SCHEMBL28015459 | 0.84 | P2RX7 (0.64) | P2RX7KDM4EALOX15TSHRACMSD | |
| SCHEMBL13043982 | 0.82 | P2RX7 (0.62) | P2RX7KDM4EALOX15TSHRACMSD | |
| SCHEMBL29709918 | 0.82 | P2RX7 (0.62) | P2RX7KDM4EALOX15TSHRACMSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 718 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119841727-A | Method for directly preparing carboxylic ester compound from aromatic aldehyde, ketone and carboxylic acid | 湖南第一师范学院 | 2025-04-18 | — | — | CN | claimed |
| CN-107333975-B | A kind of novel processing step of chromium picolinate based food additive | 淄博职业学院 | 2019-10-08 | — | — | CN | claimed |
| CN-107400256-B | A kind of preparation method of uvioresistant plastic additive | 深圳市精研科洁科技股份有限公司 | 2019-04-19 | — | — | CN | claimed |
| CN-107445941-A | The preparation method and application of triazole compound with immunosuppressive activity | 河南科技大学第附属医院 | 2017-12-08 | — | — | CN | claimed |
| CN-107400256-A | A kind of preparation method of uvioresistant plastic additive | 毛阿龙 | 2017-11-28 | — | — | CN | claimed |
| CN-107382989-A | A kind of synthetic method with oxazole ring structure immunosuppressive drug | 河南科技大学第附属医院 | 2017-11-24 | — | — | CN | claimed |
| CN-107337638-A | A kind of high-efficiency synthesis method of pyridine carboxylic acid based food additive | 侯茜茜 | 2017-11-10 | — | — | CN | claimed |
| CN-107333975-A | A kind of novel processing step of chromium picolinate based food additive | 淄博职业学院 | 2017-11-10 | — | — | CN | claimed |
| CN-107298677-A | The preparation method and application of evil azole compounds with immunosuppressive activity | 侯茜茜 | 2017-10-27 | — | — | CN | claimed |
| US-9428456-B2 | 1-[m-carboxamido(hetero)aryl-methyl]-heterocyclyl-carboxamide derivatives | ACTELION PHARMACEUTICALS LTD (CH) | 2016-08-30 | — | — | US | claimed |
| US-20130345199-A1 | 1-[M-CARBOXAMIDO(HETERO)ARYL-METHYL]-PIPERIDINE-4-CARBOXAMIDE DERIVATIVES | ACTELION PHARMACEUTICALS LTD. (CH) | 2013-12-26 | — | — | US | claimed |
| EP-2310356-B1 | ADAMANTYL DIAMIDE DERIVATIVES AND USES OF SAME | LUNDBECK & CO AS H (DK) | 2013-08-14 | — | — | EP | claimed |
| CN-102595893-A | Spirolactam derivatives and uses of same | LUNDBECK & CO AS H | 2012-07-18 | — | — | CN | claimed |
| JP-2011529057-A | — | — | 2011-12-01 | — | — | JP | claimed |
| CN-102105437-A | Adamantyl diamide derivatives and uses of same | LUNDBECK & CO AS H | 2011-06-22 | — | — | CN | claimed |
| CN-102083827-A | Thiazolidine compounds as orexin receptor antagonists | ACTELION PHARMACEUTICALS LTD | 2011-06-01 | — | — | CN | claimed |
| US-20110105491-A1 | THIAZOLIDINE COMPOUNDS AS OREXIN RECEPTOR ANTAGONISTS | ACTELION PHARMACEUTICALS LTD. (CH) | 2011-05-05 | — | — | US | claimed |
| WO-2010011570-A1 | ADAMANTYL DIAMIDE DERIVATIVES AND USES OF SAME | H. LUNDBECK A/S (DK) | 2010-01-28 | — | — | WO | claimed |
| US-20100022546-A1 | ADAMANTYL DIAMIDE DERIVATIVES AND USES OF SAME | H. LUNDBECK A/S (DK) | 2010-01-28 | — | — | US | claimed |
| WO-2010004507-A1 | THIAZOLIDINE COMPOUNDS AS OREXIN RECEPTOR ANTAGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2010-01-14 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110105491-A1 | THIAZOLIDINE COMPOUNDS AS OREXIN RECEPTOR ANTAGONISTS | HCRTR2, HCRTR1, OXTR | P2RX7 363/4885KDM4E 3641/4885ALOX15 1712/4885 |
| US-20100022546-A1 | ADAMANTYL DIAMIDE DERIVATIVES AND USES OF SAME | QDPR, ADM2, PDE3B | P2RX7 1517/4885KDM4E 2749/4885ALOX15 3886/4885 |
| US-20130345199-A1 | 1-[M-CARBOXAMIDO(HETERO)ARYL-METHYL]-PIPERIDINE-4-CARBOXAMIDE DERIVATIVES | CXCR1, CXCR5, CXCR4 | P2RX7 8/4885KDM4E 1526/4885ALOX15 3884/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.