SCHEMBL25537893

SCHEMBL25537893

CC1(C)c2c(cccc2-c2ccc(-c3ccc(-c4cc(-c5ccccc5)nc(-c5ccccc5)n4)c4ccccc34)c3ccccc23)-c2ccc3ccccc3c21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 11/20 0.40
KMT2A Q03164 11/20 0.40
MAPT P10636 9/20 0.40
ALDH1A1 P00352 9/20 0.40
HPGD P15428 9/20 0.40
NTSR1 P30989 1/20 0.40
KDM4E B2RXH2 7/20 0.39
CYP2C19 P33261 2/20 0.39
NPSR1 Q6W5P4 1/20 0.39
RXFP1 Q9HBX9 1/20 0.39
LMNA P02545 3/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
TP53 P04637 1/20 0.39
TSHR P16473 1/20 0.39
NFKB1 P19838 1/20 0.39
MAPK1 P28482 1/20 0.39
NFKB2 Q00653 1/20 0.39
RELA Q04206 1/20 0.39
ATM Q13315 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25537249 1.00 MEN1 (0.40) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL25538405 0.97 MEN1 (0.41) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL25537251 0.97 MEN1 (0.41) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL25537894 0.97 MEN1 (0.41) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL25538404 0.97 MEN1 (0.41) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL25537256 0.97 MEN1 (0.41) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL25537259 0.96 MEN1 (0.43) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL25537898 0.96 MEN1 (0.43) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL25537261 0.95 ENPP3 (0.41) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL25538409 0.94 MEN1 (0.41) MEN1KMT2AMAPTALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230167072-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-06-01 US disclosed
US-20230167072-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-06-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230167072-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE PIEZO1, LEF1, L1CAM MEN1 267/4885KMT2A 1094/4885MAPT 1595/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.