Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 17/20 | 0.86 |
| ▸ | DRD4 | P21917 | 17/20 | 0.86 |
| ▸ | DRD3 | P35462 | 15/20 | 0.86 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8042265 | 0.91 | DRD4 (0.96) | DRD2DRD4DRD3 | |
| SCHEMBL14294277 | 0.89 | DRD2 (0.79) | DRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL8042240 | 0.89 | DRD2 (0.92) | DRD2DRD4DRD3 | |
| SCHEMBL23067930 | 0.89 | DRD2 (0.92) | DRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL8053903 | 0.87 | DRD2 (0.88) | DRD2DRD4DRD3 | |
| SCHEMBL13463987 | 0.85 | DRD2 (0.79) | DRD2DRD4DRD3 | |
| SCHEMBL109524 | 0.84 | DRD2 (0.63) | DRD2DRD4DRD3TSHRKMT2A | |
| Hydrochloric Acid SCHEMBL8055383 | 0.84 | DRD2 (0.97) | DRD2DRD4DRD3 | |
| SCHEMBL24268710 | 0.84 | DRD2 (0.83) | DRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL8054953 | 0.84 | DRD2 (0.97) | DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230165848-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2023-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230165848-A1 | CHEMICAL COMPOUNDS | ATF4, XBP1, EIF2B5 | DRD2 2564/4885DRD4 1716/4885DRD3 2695/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.