SCHEMBL25538463

SCHEMBL25538463

c1ccc(-c2cccc(-c3cc(-c4ccc(-c5ccc6c(c5)C(c5ccccc5)(c5ccccc5)c5c-6ccc6ccccc56)c5ccccc45)nc(-c4ccccc4)n3)c2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.36
ALDH1A1 P00352 5/20 0.36
HPGD P15428 5/20 0.36
MEN1 O00255 4/20 0.36
KMT2A Q03164 4/20 0.36
KDM4E B2RXH2 4/20 0.36
LMNA P02545 3/20 0.36
GLA P06280 1/20 0.36
NTSR1 P30989 1/20 0.35
CYP1A1 P04798 1/20 0.33
CYP1B1 Q16678 1/20 0.33
PTGES O14684 1/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
MAPK1 P28482 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
TP53 P04637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25538623 0.97 HPGD (0.38) MAPTALDH1A1HPGDMEN1KMT2A
SCHEMBL25538459 0.96 HPGD (0.39) MAPTALDH1A1HPGDMEN1KMT2A
SCHEMBL25538624 0.96 HPGD (0.39) MAPTALDH1A1HPGDMEN1KMT2A
SCHEMBL25538622 0.94 ALDH1A1 (0.38) MAPTALDH1A1HPGDMEN1KMT2A
SCHEMBL25538461 0.94 HPGD (0.40) MAPTALDH1A1HPGDMEN1KMT2A
SCHEMBL25538551 0.94 ALDH1A1 (0.38) MAPTALDH1A1HPGDMEN1KMT2A
SCHEMBL25538468 0.94 CYP1A1 (0.40) MAPTALDH1A1HPGDMEN1KMT2A
SCHEMBL25540541 0.92 CYP1A1 (0.36) MAPTALDH1A1HPGDMEN1KMT2A
SCHEMBL25538465 0.92 ALDH1A1 (0.39) MAPTALDH1A1HPGDMEN1KMT2A
SCHEMBL25534816 0.91 MEN1 (0.41) MAPTALDH1A1HPGDMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230167072-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-06-01 US disclosed
US-20230167072-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-06-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230167072-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE PIEZO1, LEF1, L1CAM MAPT 1595/4885ALDH1A1 254/4885HPGD 3854/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.