⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25467673 | 0.66 | KDM4E (0.36) | — | |
| SCHEMBL13054401 | 0.62 | GCGR (0.36) | — | |
| SCHEMBL14226085 | 0.61 | ALDH1A1 (0.32) | — | |
| SCHEMBL12415261 | 0.61 | ALDH1A1 (0.49) | — | |
| SCHEMBL12775549 | 0.61 | KMT2A (0.37) | — | |
| SCHEMBL12904544 | 0.59 | — | — | |
| SCHEMBL12368444 | 0.58 | LMNA (0.36) | — | |
| SCHEMBL15071356 | 0.58 | ADORA2A (0.34) | — | |
| SCHEMBL18223396 | 0.57 | PDE10A (0.38) | — | |
| SCHEMBL24081519 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230151001-A9 | IMIDAZOPYRIDINE DERIVATIVES AND AZA-IMIDAZOPYRIDINE DERIVATIVES AS JANUS KINASE 2 INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2023-05-18 | — | — | US | disclosed |