Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19036911 | 0.76 | KDM4E (0.45) | ALDH1A1KDM4ESMN1; SMN2PKMPTGS2 | |
| SCHEMBL7793045 | 0.73 | PKM (0.42) | ALDH1A1KDM4ESMN1; SMN2PKMPTGS2 | |
| SCHEMBL26006992 | 0.71 | ALDH1A1 (0.31) | ALDH1A1KDM4ESMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL13134044 | 0.70 | PDE10A (0.33) | PDE10A | |
| SCHEMBL15550878 | 0.69 | — | — | |
| SCHEMBL14341760 | 0.68 | KDM4E (0.42) | ALDH1A1KDM4ESMN1; SMN2MAPTHPGD | |
| SCHEMBL15062063 | 0.68 | KDM4E (0.39) | ALDH1A1KDM4ESMN1; SMN2PKMPTGS2 | |
| SCHEMBL19036912 | 0.67 | KDM4E (0.41) | ALDH1A1KDM4ESMN1; SMN2MAPTHPGD | |
| SCHEMBL15339542 | 0.67 | KDM4E (0.51) | ALDH1A1KDM4ESMN1; SMN2PKMPTGS2 | |
| SCHEMBL18223396 | 0.67 | PDE10A (0.38) | ALDH1A1KDM4ESMN1; SMN2HPGDPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8853125-B2 | Pyrazole compounds for controlling invertebrate pests | BASF SE (DE) | 2014-10-07 | — | — | US | disclosed |
| US-20110173726-A1 | Pyrazole Compounds for Controlling Invertebrate Pests | BASF SE (DE) | 2011-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110173726-A1 | Pyrazole Compounds for Controlling Invertebrate Pests | PRXL2A, GRIN2C, GRIN2A | ALDH1A1 1791/4885KDM4E 3903/4885SMN1; SMN2 3168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.