SCHEMBL25540640

SCHEMBL25540640

c1ccc(-c2cc(-c3ccccc3)nc(-c3ccc(-c4ccc5c(c4)-c4ccc6ccccc6c4C5(c4ccccc4)c4ccccc4)c4ccccc34)n2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.37
ALDH1A1 P00352 6/20 0.37
HPGD P15428 6/20 0.37
KDM4E B2RXH2 4/20 0.37
KMT2A Q03164 6/20 0.37
MEN1 O00255 5/20 0.37
LMNA P02545 2/20 0.36
GLA P06280 1/20 0.36
CYP1A1 P04798 2/20 0.35
CYP1B1 Q16678 2/20 0.35
NTSR1 P30989 1/20 0.34
PTGES O14684 1/20 0.33
SMN1; SMN2 Q16637 3/20 0.32
CHRNA1 P02708 1/20 0.32
CHRNG P07510 1/20 0.32
CHRNB1 P11230 1/20 0.32
CHRNB2 P17787 1/20 0.32
SLC6A2 P23975 1/20 0.32
CHRNB4 P30926 1/20 0.32
SLC6A4 P31645 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25540766 0.99 MAPT (0.36) MAPTALDH1A1HPGDKDM4EKMT2A
SCHEMBL25540642 0.99 MAPT (0.36) MAPTALDH1A1HPGDKDM4EKMT2A
SCHEMBL25540763 0.98 MAPT (0.36) MAPTALDH1A1HPGDKDM4EKMT2A
SCHEMBL25540644 0.96 ALDH1A1 (0.36) MAPTALDH1A1HPGDKDM4EKMT2A
SCHEMBL25540650 0.96 CYP1A1 (0.42) MAPTALDH1A1HPGDKDM4EKMT2A
SCHEMBL25540647 0.96 MAPT (0.34) MAPTALDH1A1HPGDKDM4EKMT2A
SCHEMBL25538660 0.96 MAPT (0.34) MAPTALDH1A1HPGDKDM4EKMT2A
SCHEMBL25540758 0.95 MAPT (0.38) MAPTALDH1A1HPGDKDM4EKMT2A
SCHEMBL25540645 0.95 MAPT (0.36) MAPTALDH1A1HPGDKDM4EKMT2A
SCHEMBL25540539 0.93 ALDH1A1 (0.38) MAPTALDH1A1HPGDKDM4EKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230167072-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-06-01 US disclosed
US-20230167072-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-06-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230167072-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE PIEZO1, LEF1, L1CAM MAPT 1595/4885ALDH1A1 254/4885HPGD 3854/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.