SCHEMBL25540641

SCHEMBL25540641

O=[N+]([O-])c1cc(Br)c(-n2c3ccccc3c3cc(-c4ccc5c(c4)c4ccccc4n5-c4ccccc4)ccc32)c(Br)c1

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.44
ATM Q13315 2/20 0.43
KDM4E B2RXH2 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
MEN1 O00255 5/20 0.42
KMT2A Q03164 5/20 0.42
ALDH1A1 P00352 4/20 0.42
MPI P34949 1/20 0.42
APOBEC3G Q9HC16 1/20 0.42
LMNA P02545 3/20 0.41
HTT P42858 1/20 0.40
POLB P06746 2/20 0.40
PKM P14618 1/20 0.39
SIRT2 Q8IXJ6 1/20 0.38
PDE4A P27815 1/20 0.38
PDE4B Q07343 1/20 0.38
PDE4C Q08493 1/20 0.38
PDE4D Q08499 1/20 0.38
HSP90AA1 P07900 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25540489 0.93 MAPT (0.46) MAPTATML3MBTL1MEN1KMT2A
SCHEMBL25540560 0.92 MAPT (0.41) MAPTATMKDM4EL3MBTL1MEN1
SCHEMBL25540526 0.88 MAPT (0.48) MAPTATMKDM4EL3MBTL1MEN1
SCHEMBL25540636 0.86 MAPT (0.44) MAPTATMKDM4EL3MBTL1MEN1
SCHEMBL25540707 0.84 MAPT (0.45) MAPTATMMEN1KMT2ALMNA
SCHEMBL19642950 0.84 ATM (0.46) MAPTATMKDM4EL3MBTL1MEN1
SCHEMBL19119484 0.83 ATM (0.45) MAPTATMKDM4EL3MBTL1MEN1
SCHEMBL11981037 0.80 ALDH1A1 (0.53) MAPTATMKDM4EL3MBTL1MEN1
SCHEMBL25540691 0.79 MAPT (0.39) MAPTATMKDM4EL3MBTL1MEN1
SCHEMBL31548612 0.79 MAPT (0.68) MAPTATMKDM4EL3MBTL1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230159570-A1 LIGHT-EMITTING DEVICE INCLUDING HETEROCYCLIC COMPOUND, ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE, AND THE HETEROCYCLIC COMPOUND SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230159570-A1 LIGHT-EMITTING DEVICE INCLUDING HETEROCYCLIC COMPOUND, ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE, AND THE HETEROCYCLIC COMPOUND CRY1, CYP1A1, NQO1 MAPT 3198/4885ATM 3960/4885KDM4E 3633/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.