SCHEMBL25540707

SCHEMBL25540707

O=[N+]([O-])c1cc(Br)c(-n2c3ccccc3c3cc(-c4ccc5oc6ccccc6c5c4)ccc32)c(Br)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.45
MEN1 O00255 4/20 0.45
KMT2A Q03164 4/20 0.45
TNKS O95271 1/20 0.40
PARP1 P09874 1/20 0.40
CSNK2A2 P19784 1/20 0.40
CSNK2B P67870 1/20 0.40
CSNK2A1 P68400 1/20 0.40
TNKS2 Q9H2K2 1/20 0.40
PARP2 Q9UGN5 1/20 0.40
LMNA P02545 2/20 0.39
POLB P06746 1/20 0.37
ATM Q13315 1/20 0.37
GABRP O00591 4/20 0.36
GABRD O14764 4/20 0.36
GABRA1 P14867 4/20 0.36
GABRB1 P18505 4/20 0.36
GABRG2 P18507 4/20 0.36
GABRB3 P28472 4/20 0.36
GABRA5 P31644 4/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25540489 0.86 MAPT (0.46) MAPTMEN1KMT2ALMNAPOLB
SCHEMBL25540701 0.86 MAPT (0.44) MAPTMEN1KMT2ATNKSPARP1
SCHEMBL25540641 0.84 MAPT (0.44) MAPTMEN1KMT2ALMNAPOLB
SCHEMBL25540560 0.81 MAPT (0.41) MAPTMEN1KMT2ALMNAPOLB
SCHEMBL25540526 0.79 MAPT (0.48) MAPTMEN1KMT2ALMNAPOLB
SCHEMBL21092964 0.77 MAPT (0.41) MAPTMEN1KMT2ATNKSPARP1
SCHEMBL11987362 0.74 KDM4E (0.46) MAPTMEN1KMT2ALMNAATM
SCHEMBL24639786 0.74 TNKS (0.42) MAPTMEN1KMT2ATNKSATM
SCHEMBL23918891 0.73 MAPT (0.42) MAPTMEN1KMT2ALMNAATM
SCHEMBL11885215 0.73 KDM4E (0.42) MAPTMEN1KMT2ALMNAATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230159570-A1 LIGHT-EMITTING DEVICE INCLUDING HETEROCYCLIC COMPOUND, ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE, AND THE HETEROCYCLIC COMPOUND SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230159570-A1 LIGHT-EMITTING DEVICE INCLUDING HETEROCYCLIC COMPOUND, ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE, AND THE HETEROCYCLIC COMPOUND CRY1, CYP1A1, NQO1 MAPT 3198/4885MEN1 241/4885KMT2A 1759/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.