Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.65 |
| ▸ | HRH2 | P25021 | 3/20 | 0.65 |
| ▸ | HRH1 | P35367 | 3/20 | 0.65 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19047571 | 0.94 | HRH3 (0.68) | HRH3HRH2HRH1SIGMAR1KDM4E | |
| SCHEMBL22639936 | 0.86 | SIGMAR1 (0.76) | HRH3HRH2HRH1SIGMAR1KDM4E | |
| SCHEMBL25539094 | 0.85 | HRH3 (0.69) | HRH3HRH2HRH1SIGMAR1 | |
| SCHEMBL7397226 | 0.85 | HRH3 (0.65) | HRH3HRH2HRH1SIGMAR1 | |
| SCHEMBL19705172 | 0.85 | SIGMAR1 (0.74) | HRH3HRH2HRH1SIGMAR1 | |
| SCHEMBL6948464 | 0.84 | TMEM97 (0.67) | HRH3HRH2HRH1SIGMAR1KDM4E | |
| SCHEMBL8109504 | 0.84 | TMEM97 (0.67) | HRH3HRH2HRH1SIGMAR1KDM4E | |
| Hydrochloric Acid SCHEMBL19692547 | 0.84 | SIGMAR1 (0.74) | HRH3HRH2HRH1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL8055586 | 0.84 | HRH3 (0.64) | HRH3HRH2HRH1SIGMAR1 | |
| SCHEMBL25538081 | 0.82 | HRH3 (0.63) | HRH3HRH2HRH1SIGMAR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230165848-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2023-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230165848-A1 | CHEMICAL COMPOUNDS | ATF4, XBP1, EIF2B5 | HRH3 1136/4885HRH2 1726/4885HRH1 1588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.