Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14507915 | 0.79 | THRB (0.35) | CES1 | |
| SCHEMBL12761116 | 0.79 | FDPS (0.39) | FDPS | |
| SCHEMBL10015864 | 0.78 | — | — | |
| SCHEMBL2097971 | 0.77 | FDPS (0.35) | FDPS | |
| SCHEMBL18926533 | 0.74 | THRB (0.37) | — | |
| SCHEMBL9947119 | 0.74 | FDPS (0.37) | FDPS | |
| SCHEMBL10510271 | 0.74 | CES1 (0.50) | HTTCES1 | |
| SCHEMBL10507590 | 0.74 | CES1 (0.50) | HTTCES1 | |
| SCHEMBL11612056 | 0.73 | FDPS (0.42) | FDPS | |
| SCHEMBL10015858 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086383-A1 | SELECT KRAS G12C INHIBITORS AND USES THEREOF | 1200 PHARMA LLC (US) | 2023-05-19 | — | — | WO | disclosed |