Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 4/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10313065 | 0.95 | FDPS (0.39) | FDPSDNM1MEN1KMT2AALDH1A1 | |
| SCHEMBL13696918 | 0.91 | FDPS (0.41) | FDPSDNM1MEN1KMT2AALDH1A1 | |
| SCHEMBL8432610 | 0.90 | FDPS (0.39) | FDPSDNM1MEN1KMT2AALDH1A1 | |
| SCHEMBL19283464 | 0.90 | FDPS (0.39) | FDPSDNM1MEN1KMT2AALDH1A1 | |
| SCHEMBL12761116 | 0.90 | FDPS (0.39) | FDPSDNM1MEN1KMT2AALDH1A1 | |
| SCHEMBL16500149 | 0.89 | FDPS (0.35) | FDPS | |
| SCHEMBL27421 | 0.88 | DNM1 (0.42) | FDPSDNM1MEN1KMT2AALDH1A1 | |
| SCHEMBL3620823 | 0.88 | FDPS (0.42) | FDPSDNM1MEN1KMT2AALDH1A1 | |
| SCHEMBL7628517 | 0.88 | DNM1 (0.36) | FDPSDNM1MEN1KMT2AALDH1A1 | |
| SCHEMBL28654242 | 0.88 | DNM1 (0.42) | FDPSDNM1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8562966-B2 | End-modified poly(beta-amino esters) and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-10-22 | — | — | US | disclosed |
| US-20120149630-A1 | END-MODIFIED POLY(BETA-AMINO ESTERS) AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-06-14 | — | — | US | disclosed |
| US-20080242626-A1 | End-Modified Poly(beta-amino esters) and Uses Thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2008-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149630-A1 | END-MODIFIED POLY(BETA-AMINO ESTERS) AND USES THEREOF | PARN, PARG, POLL | FDPS 3566/4885DNM1 612/4885MEN1 2403/4885 |
| US-20080242626-A1 | End-Modified Poly(beta-amino esters) and Uses Thereof | PARN, PARG, POLL | FDPS 3566/4885DNM1 612/4885MEN1 2403/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.