Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA1 | P02708 | 1/20 | 0.38 |
| ▸ | CHRNG | P07510 | 1/20 | 0.38 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | CHRND | Q07001 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | SLC16A3 | O15427 | 4/20 | 0.38 |
| ▸ | SLC16A1 | P53985 | 4/20 | 0.38 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21747402 | 0.89 | RECQL (0.38) | JAK2SLC16A3SLC16A1MCTS1HTR1A | |
| SCHEMBL21765700 | 0.88 | JAK2 (0.38) | JAK2HTR1ADRD2HTR2AHTR7 | |
| SCHEMBL21747276 | 0.87 | ALDH1A1 (0.42) | JAK2SLC16A3SLC16A1MCTS1HTR1A | |
| SCHEMBL25543982 | 0.87 | P2RX3 (0.37) | SLC6A3SMN1; SMN2MAPTNPC1ALDH1A1 | |
| SCHEMBL25543943 | 0.83 | EGLN1 (0.40) | SLC6A2SLC6A3SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL25544014 | 0.82 | EGLN1 (0.39) | SLC6A2SLC6A3SMN1; SMN2MAPTPOLB | |
| SCHEMBL25543987 | 0.78 | EGLN1 (0.36) | SLC6A3SMN1; SMN2MAPTALDH1A1HPGD | |
| SCHEMBL25544030 | 0.78 | EGLN1 (0.38) | MAPTALDH1A1HPGDNPSR1 | |
| SCHEMBL25543949 | 0.77 | EGLN1 (0.35) | SMN1; SMN2POLBALDH1A1TSHR | |
| SCHEMBL25543967 | 0.77 | KDM4E (0.36) | SLC6A3SLC16A3SLC16A1MCTS1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230257379-A1 | INDOLIZINE DERIVATIVES AND THEIR APPLICATION IN MEDICINE | KIND PHARMACEUTICAL (CN) | 2023-08-17 | — | — | US | disclosed |
| US-20230242527-A1 | INDOLIZINE DERIVATIVES AND THEIR APPLICATION IN MEDICINE | KIND PHARMACEUTICAL (CN) | 2023-08-03 | — | — | US | disclosed |
| US-11655249-B2 | Indolizine derivatives and their application in medicine | KIND PHARMACEUTICAL (CN) | 2023-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230257379-A1 | INDOLIZINE DERIVATIVES AND THEIR APPLICATION IN MEDICINE | INMT, IDO1, IDO2 | CHRNA1 1561/4885CHRNG 3305/4885CHRNB1 1652/4885 |
| US-20230242527-A1 | INDOLIZINE DERIVATIVES AND THEIR APPLICATION IN MEDICINE | INMT, IDO1, IDO2 | CHRNA1 1561/4885CHRNG 3305/4885CHRNB1 1652/4885 |
| US-11655249-B2 | Indolizine derivatives and their application in medicine | INMT, IDO1, IDO2 | CHRNA1 1561/4885CHRNG 3305/4885CHRNB1 1652/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.