SCHEMBL25544161

SCHEMBL25544161

N#Cc1ccc(-c2ccc(N(c3ccc(-c4ccc(C#N)cc4)cc3)c3ccc(-c4ccc(C#N)cc4)cc3)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP3 P08254 1/20 0.56
KIF11 P52732 3/20 0.50
CA12 O43570 2/20 0.47
CA2 P00918 2/20 0.47
CA9 Q16790 2/20 0.47
CA1 P00915 1/20 0.47
TSHR P16473 2/20 0.46
HSD17B10 Q99714 1/20 0.46
CYP11B2 P19099 1/20 0.45
CYP2A6 P11509 2/20 0.44
ENPP2 Q13822 1/20 0.44
ALDH1A1 P00352 2/20 0.44
CA3 P07451 1/20 0.44
CA6 P23280 1/20 0.44
CA14 Q9ULX7 1/20 0.44
NOTUM Q6P988 1/20 0.41
HRH3 Q9Y5N1 2/20 0.40
PTPN5 P54829 1/20 0.40
LOXL2 Q9Y4K0 1/20 0.39
HDAC2 Q92769 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25543233 1.00 MMP3 (0.56) MMP3KIF11CA12CA2CA9
SCHEMBL995812 0.92 CA2 (0.50) MMP3KIF11CA12CA2CA9
SCHEMBL25544242 0.91 TSHR (0.52) MMP3KIF11CA12CA2CA9
SCHEMBL15807463 0.91 TSHR (0.52) MMP3KIF11CA12CA2CA9
SCHEMBL10029850 0.91 TSHR (0.52) MMP3KIF11CA12CA2CA9
SCHEMBL25543620 0.91 TSHR (0.52) MMP3KIF11CA12CA2CA9
SCHEMBL16484549 0.91 TSHR (0.52) MMP3KIF11CA12CA2CA9
SCHEMBL16484551 0.91 TSHR (0.52) MMP3KIF11CA12CA2CA9
SCHEMBL15807473 0.91 TSHR (0.52) MMP3KIF11CA12CA2CA9
SCHEMBL10029827 0.91 TSHR (0.52) MMP3KIF11CA12CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230301181-A1 TERTIARY AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME LAPTO CO., LTD. (KR) 2023-09-21 US disclosed
EP-4183784-A1 TERTIARY AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME Lapto Co., Ltd. (KR) 2023-05-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230301181-A1 TERTIARY AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME SAT1, FTO, SETDB1 MMP3 4768/4885KIF11 2221/4885CA12 3594/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.