SCHEMBL25544455

SCHEMBL25544455

N#Cc1cc(C#N)cc(-c2ccc(N(c3ccc(-c4nc5ccccc5s4)cc3)c3ccc(-c4cccc5c4oc4ccccc45)cc3)cc2)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ APP P05067 7/20 0.40
▸ MAPT P10636 5/20 0.39
▸ ALDH1A1 P00352 2/20 0.39
▸ HPGD P15428 2/20 0.39
▸ POLB P06746 1/20 0.39
▸ CTDSP1 Q9GZU7 1/20 0.39
▸ MMP9 P14780 1/20 0.38
▸ MMP8 P22894 1/20 0.38
▸ MEN1 O00255 1/20 0.37
▸ KMT2A Q03164 1/20 0.37
▸ NPSR1 Q6W5P4 1/20 0.37
▸ ALOX5 P09917 1/20 0.37
▸ THRB P10828 1/20 0.37
▸ ATP4A P20648 3/20 0.36
▸ ATP4B P51164 3/20 0.36
▸ RAB9A P51151 2/20 0.36
▸ PAX8 Q06710 1/20 0.36
▸ NOD2 Q9HC29 1/20 0.36
▸ L3MBTL1 Q9Y468 1/20 0.36
▸ KDM4E B2RXH2 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25543326 0.96 APP (0.41) APPMAPTALDH1A1HPGDPOLB
SCHEMBL25544171 0.94 APP (0.42) APPMAPTALDH1A1HPGDPOLB
SCHEMBL25543240 0.93 APP (0.43) APPMAPTALDH1A1HPGDPOLB
SCHEMBL24331847 0.91 ALOX5 (0.41) APPMAPTALDH1A1HPGDPOLB
SCHEMBL23328456 0.89 APP (0.50) APPMAPTALDH1A1HPGDPOLB
SCHEMBL25544625 0.89 APP (0.40) APPMAPTALDH1A1HPGDPOLB
SCHEMBL25543630 0.88 APP (0.47) APPMAPTALDH1A1HPGDPOLB
SCHEMBL25543490 0.88 APP (0.40) APPMAPTALDH1A1HPGDPOLB
SCHEMBL24331828 0.87 ALOX5 (0.41) APPMAPTALDH1A1HPGDPOLB
SCHEMBL25543158 0.87 APP (0.48) APPMAPTALDH1A1HPGDPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230301181-A1 TERTIARY AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME LAPTO CO., LTD. (KR) 2023-09-21 — — US disclosed
US-20230301181-A1 TERTIARY AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME LAPTO CO., LTD. (KR) 2023-09-21 — — US disclosed
EP-4183784-A1 TERTIARY AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME Lapto Co., Ltd. (KR) 2023-05-24 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230301181-A1 TERTIARY AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME SAT1, FTO, SETDB1 APP 2445/4885MAPT 745/4885ALDH1A1 16/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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