SCHEMBL25543158

SCHEMBL25543158

c1ccc(N(c2ccc(-c3nc4ccccc4s3)cc2)c2ccc(-c3cccc4c3oc3ccccc34)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ APP P05067 6/20 0.48
▸ MAPT P10636 5/20 0.42
▸ RAB9A P51151 4/20 0.42
▸ KDM4E B2RXH2 3/20 0.42
▸ NPC1 O15118 3/20 0.42
▸ ALDH1A1 P00352 2/20 0.42
▸ GLA P06280 2/20 0.42
▸ GAA P10253 2/20 0.42
▸ MMP9 P14780 2/20 0.42
▸ MMP8 P22894 2/20 0.42
▸ LMNA P02545 1/20 0.42
▸ POLB P06746 1/20 0.42
▸ HPGD P15428 1/20 0.42
▸ CTDSP1 Q9GZU7 1/20 0.42
▸ ALOX5 P09917 1/20 0.41
▸ MEN1 O00255 2/20 0.41
▸ KMT2A Q03164 2/20 0.41
▸ NPSR1 Q6W5P4 1/20 0.41
▸ PAX8 Q06710 2/20 0.40
▸ THRB P10828 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23328456 0.98 APP (0.50) APPMAPTRAB9AKDM4ENPC1
SCHEMBL25543630 0.97 APP (0.47) APPMAPTRAB9AKDM4ENPC1
SCHEMBL25543830 0.92 RAB9A (0.51) APPMAPTRAB9AKDM4ENPC1
SCHEMBL25543240 0.90 APP (0.43) APPMAPTRAB9AKDM4ENPC1
SCHEMBL25544171 0.89 APP (0.42) APPMAPTRAB9AKDM4ENPC1
SCHEMBL25543326 0.88 APP (0.41) APPMAPTRAB9AKDM4ENPC1
SCHEMBL29299105 0.88 APP (0.43) APPMAPTRAB9AKDM4ENPC1
SCHEMBL25543490 0.87 APP (0.40) APPMAPTRAB9AKDM4ENPC1
SCHEMBL25544455 0.87 APP (0.40) APPMAPTRAB9AKDM4ENPC1
SCHEMBL24332297 0.87 ALOX5 (0.47) APPMAPTRAB9AKDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230301181-A1 TERTIARY AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME LAPTO CO., LTD. (KR) 2023-09-21 — — US disclosed
US-20230301181-A1 TERTIARY AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME LAPTO CO., LTD. (KR) 2023-09-21 — — US disclosed
EP-4183784-A1 TERTIARY AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME Lapto Co., Ltd. (KR) 2023-05-24 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230301181-A1 TERTIARY AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME SAT1, FTO, SETDB1 APP 2445/4885MAPT 745/4885RAB9A 2173/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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