Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.49 |
| ▸ | XDH | P47989 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 3/20 | 0.41 |
| ▸ | PPARA | Q07869 | 3/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30080246 | 0.90 | ALKBH1 (0.51) | ALKBH1XDHUSP2ALDH1A1CYP1A2 | |
| SCHEMBL23767729 | 0.90 | ALKBH1 (0.51) | ALKBH1XDHUSP2ALDH1A1CYP1A2 | |
| SCHEMBL23767728 | 0.88 | ALKBH1 (0.47) | ALKBH1XDHUSP2ALDH1A1CYP1A2 | |
| SCHEMBL23767730 | 0.88 | ALKBH1 (0.49) | ALKBH1XDHUSP2ALDH1A1CYP1A2 | |
| SCHEMBL30080394 | 0.88 | ALKBH1 (0.49) | ALKBH1XDHUSP2ALDH1A1CYP1A2 | |
| SCHEMBL23753904 | 0.84 | SMN1; SMN2 (0.54) | ALKBH1XDHMAOBALDH1A1PPARD | |
| SCHEMBL7464319 | 0.82 | PDE5A (0.50) | ALKBH1XDHUSP2ALDH1A1CYP1A2 | |
| SCHEMBL25544417 | 0.78 | XDH (0.37) | XDHALDH1A1CYP1A2CYP3A4MAPK1 | |
| SCHEMBL1163902 | 0.77 | XDH (0.45) | ALKBH1XDHMAOBCYP1A2CYP3A4 | |
| SCHEMBL30756486 | 0.74 | MAOB (0.53) | ALKBH1MAOBALDH1A1ALOX5GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230165846-A1 | HETEROCYCLIC GLP-1 AGONISTS | GASHERBRUM BIO, INC. | 2023-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230165846-A1 | HETEROCYCLIC GLP-1 AGONISTS | GLP1R, GIPR, GCGR | ALKBH1 4349/4885XDH 1324/4885MAOB 2452/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.