Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | G6PD | P11413 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2553161 | 0.82 | ENPP2 (0.47) | ENPP2CA2PTGS2 | |
| SCHEMBL30816185 | 0.76 | ENPP2 (0.34) | ENPP2CYP2C19CYP1A2ALDH1A1MEN1 | |
| SCHEMBL27159787 | 0.76 | ENPP2 (0.34) | ENPP2CYP2C19CYP1A2ALDH1A1MEN1 | |
| SCHEMBL2555834 | 0.76 | CCR5 (0.42) | CYP2C19CYP1A2SLC6A4KMT2AGAA | |
| SCHEMBL19214301 | 0.75 | ENPP2 (0.50) | ENPP2CA2 | |
| SCHEMBL30643101 | 0.73 | TTR (0.46) | ENPP2CYP2C19CYP1A2SLC6A4ALDH1A1 | |
| SCHEMBL30643134 | 0.73 | KDM4E (0.44) | CYP2C19CYP1A2SLC6A4ALDH1A1MEN1 | |
| SCHEMBL2552371 | 0.73 | SLC6A4 (0.39) | CYP2C19CYP1A2SLC6A4ALDH1A1MEN1 | |
| SCHEMBL4010773 | 0.73 | ENPP2 (0.52) | ENPP2ALDH1A1GAAL3MBTL1CA2 | |
| SCHEMBL24804602 | 0.73 | HSD17B10 (0.41) | ENPP2SLC6A4ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011123937-A1 | KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME | UNIVERSITY HEALTH NETWORK (CA) | 2011-10-13 | — | — | WO | disclosed |