Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LPL | P06858 | 1/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23852735 | 0.85 | L3MBTL1 (0.53) | ENPP2CA2L3MBTL1LPLLIPG | |
| SCHEMBL19214301 | 0.79 | ENPP2 (0.50) | ENPP2CA2LPLLIPGCA1 | |
| SCHEMBL20093239 | 0.79 | ENPP2 (0.50) | ENPP2CA2L3MBTL1LPLLIPG | |
| SCHEMBL2553161 | 0.77 | ENPP2 (0.47) | ENPP2CA2LPLLIPGCA1 | |
| SCHEMBL20399722 | 0.76 | ENPP2 (0.50) | ENPP2L3MBTL1LMNATTR | |
| SCHEMBL520332 | 0.76 | ENPP2 (0.50) | ENPP2CA2L3MBTL1LPLLIPG | |
| SCHEMBL30311154 | 0.73 | ENPP2 (0.47) | ENPP2CA2L3MBTL1ALDH1A1LMNA | |
| SCHEMBL25301879 | 0.73 | ENPP2 (0.47) | ENPP2CA2CA1GAA | |
| SCHEMBL23884760 | 0.73 | ENPP2 (0.47) | ENPP2CA2L3MBTL1ALDH1A1LMNA | |
| SCHEMBL29613207 | 0.73 | NPC1 (0.44) | ENPP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074098-A2 | QUINOLINE COMPOUNDS | Wyeth (US) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008049047-A2 | QUINOLINE COMPOUNDS | WYETH (US) | 2008-04-24 | — | — | WO | disclosed |