SCHEMBL25544623

SCHEMBL25544623

N#Cc1ccc(N(c2ccc(-c3ccc(C#N)c(C#N)c3)cc2)c2ccc(-c3cccc4c3oc3ccccc34)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.44
TNKS O95271 1/20 0.40
PRKDC P78527 4/20 0.39
GGPS1 O95749 1/20 0.34
CCNT1 O60563 1/20 0.33
CDK9 P50750 1/20 0.33
PTGES2 Q9H7Z7 1/20 0.32
PGR P06401 2/20 0.32
AR P10275 2/20 0.32
PDK2 Q15119 1/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
SCN9A Q15858 1/20 0.31
PIM1 P11309 1/20 0.31
CSNK2A2 P19784 1/20 0.31
CSNK2B P67870 1/20 0.31
PIM3 Q86V86 1/20 0.31
PIM2 Q9P1W9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25544248 0.96 ALOX5 (0.44) ALOX5TNKSPRKDCGGPS1CCNT1
SCHEMBL23328768 0.96 ALOX5 (0.47) ALOX5TNKSPRKDCGGPS1CCNT1
SCHEMBL25544526 0.96 ALOX5 (0.47) ALOX5TNKSPRKDCGGPS1CCNT1
SCHEMBL25543316 0.95 ALOX5 (0.44) ALOX5TNKSPRKDCGGPS1CCNT1
SCHEMBL25543726 0.94 ALOX5 (0.45) ALOX5TNKSPRKDCGGPS1CCNT1
SCHEMBL25544697 0.94 ALOX5 (0.45) ALOX5TNKSPRKDCGGPS1CCNT1
SCHEMBL25544170 0.91 ALOX5 (0.48) ALOX5TNKSPRKDCGGPS1CCNT1
SCHEMBL25544085 0.91 ALOX5 (0.48) ALOX5TNKSPRKDCGGPS1CCNT1
SCHEMBL23328767 0.91 ALOX5 (0.48) ALOX5TNKSPRKDCGGPS1CCNT1
SCHEMBL25544696 0.91 ALOX5 (0.43) ALOX5TNKSPRKDCGGPS1CCNT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230301181-A1 TERTIARY AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME LAPTO CO., LTD. (KR) 2023-09-21 US disclosed
EP-4183784-A1 TERTIARY AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME Lapto Co., Ltd. (KR) 2023-05-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230301181-A1 TERTIARY AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME SAT1, FTO, SETDB1 ALOX5 2036/4885TNKS 617/4885PRKDC 2559/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.