SCHEMBL25544693

SCHEMBL25544693

N#Cc1ccc(-c2ccc(N(c3ccc(-c4ccncc4)cc3)c3ccc(-c4ccncc4)cc3)cc2)cc1C#N

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 1/20 0.46
PIK3CA P42336 1/20 0.46
PIK3CB P42338 1/20 0.46
CDK8 P49336 2/20 0.46
GSK3B P49841 2/20 0.46
PRKACA P17612 1/20 0.46
CLK2 P49760 1/20 0.46
GSK3A P49840 1/20 0.46
CDK9 P50750 1/20 0.46
CDK5 Q00535 1/20 0.46
PRKCQ Q04759 1/20 0.46
ROCK1 Q13464 1/20 0.46
DYRK1A Q13627 1/20 0.46
LRRK2 Q5S007 1/20 0.46
CLK4 Q9HAZ1 1/20 0.46
DYRK1B Q9Y463 1/20 0.46
MAPT P10636 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
CCNC P24863 1/20 0.40
ALDH1A1 P00352 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25543963 1.00 PIK3CD (0.46) PIK3CDPIK3CAPIK3CBCDK8GSK3B
SCHEMBL25548561 0.93 MAPT (0.43) PIK3CDPIK3CAPIK3CBCDK8GSK3B
SCHEMBL17955208 0.89 ALDH1A1 (0.42) ALDH1A1KDM4EHTTRXFP1LMNA
SCHEMBL25548560 0.86 ALDH1A1 (0.40) ALDH1A1KDM4EHTTRXFP1LMNA
SCHEMBL25543638 0.83 ALDH1A1 (0.53) SMN1; SMN2ALDH1A1KDM4EHTTRXFP1
SCHEMBL25544534 0.83 MMP3 (0.42) ALDH1A1KDM4EHTTRXFP1LMNA
SCHEMBL25544760 0.83 ALDH1A1 (0.53) SMN1; SMN2ALDH1A1KDM4EHTTRXFP1
SCHEMBL25543166 0.83 ALDH1A1 (0.49) CDK8GSK3BPRKACACLK2GSK3A
SCHEMBL25544241 0.83 MMP3 (0.42) ALDH1A1KDM4EHTTRXFP1LMNA
SCHEMBL25543246 0.83 MMP3 (0.42) ALDH1A1KDM4EHTTRXFP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230301181-A1 TERTIARY AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME LAPTO CO., LTD. (KR) 2023-09-21 US disclosed
US-20230301181-A1 TERTIARY AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME LAPTO CO., LTD. (KR) 2023-09-21 US disclosed
EP-4183784-A1 TERTIARY AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME Lapto Co., Ltd. (KR) 2023-05-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230301181-A1 TERTIARY AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME SAT1, FTO, SETDB1 PIK3CD 4770/4885PIK3CA 4786/4885PIK3CB 4843/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.