Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | ALOX15B | O15296 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11386185 | 0.85 | CYP1A2 (0.51) | TP53THRBSMN1; SMN2L3MBTL1CYP1A2 | |
| Hydrochloric Acid SCHEMBL11377342 | 0.85 | POLB (0.54) | TP53THRBSMN1; SMN2L3MBTL1CYP1A2 | |
| SCHEMBL22471127 | 0.83 | NR4A1 (0.62) | TP53THRBSMN1; SMN2L3MBTL1CYP1A2 | |
| SCHEMBL25545181 | 0.83 | TP53 (0.51) | TP53THRBSMN1; SMN2L3MBTL1CYP1A2 | |
| Hydrochloric Acid SCHEMBL11376841 | 0.81 | CYP1A2 (0.57) | TP53THRBSMN1; SMN2L3MBTL1CYP1A2 | |
| SCHEMBL24943943 | 0.81 | L3MBTL1 (0.61) | TP53THRBSMN1; SMN2L3MBTL1CYP1A2 | |
| SCHEMBL24943934 | 0.77 | L3MBTL1 (0.77) | TP53THRBSMN1; SMN2L3MBTL1CYP1A2 | |
| SCHEMBL18418799 | 0.74 | SMN1; SMN2 (0.51) | SMN1; SMN2L3MBTL1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11381134 | 0.73 | CYP1A2 (0.52) | TP53THRBSMN1; SMN2L3MBTL1CYP1A2 | |
| SCHEMBL6608437 | 0.73 | NOTUM (0.41) | TP53THRBSMN1; SMN2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081967-A1 | COMPOUNDS AND USES THEREFOR | THE UNIVERSITY OF WESTERN AUSTRALIA (AU) | 2023-05-19 | — | — | WO | disclosed |