SCHEMBL2554594

SCHEMBL2554594

C#CC1CC(=O)C=C2CC[C@H]3[C@@H]4CC[C@H](O)[C@@]4(C)CC[C@@H]3[C@]21C

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 11/20 0.60
AR P10275 6/20 0.60
SHBG P04278 5/20 0.60
LMNA P02545 3/20 0.60
HSD17B10 Q99714 3/20 0.60
NR3C1 P04150 2/20 0.60
PGR P06401 2/20 0.60
SERPINA6 P08185 2/20 0.60
CYP3A4 P08684 2/20 0.60
TSHR P16473 2/20 0.60
SNCA P37840 2/20 0.60
CACNA1C Q13936 2/20 0.60
CYP51A1 Q16850 2/20 0.60
GPBAR1 Q8TDU6 2/20 0.60
SIGMAR1 Q99720 2/20 0.60
MAPT P10636 1/20 0.60
MAPK1 P28482 1/20 0.60
OR51E2 Q9H255 1/20 0.60
ESR2 Q92731 4/20 0.55
ESR1 P03372 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28201393 0.89 CYP19A1 (0.60) CYP19A1ARSHBGLMNAHSD17B10
SCHEMBL9436548 0.88 CYP19A1 (0.59) CYP19A1ARSHBGLMNAHSD17B10
SCHEMBL3633398 0.87 CYP19A1 (0.52) CYP19A1ARSHBGLMNAHSD17B10
SCHEMBL3331322 0.86 ALDH1A1 (0.62) ARSHBGLMNAHSD17B10NR3C1
SCHEMBL4419947 0.86 CYP19A1 (0.68) CYP19A1ARSHBGLMNAHSD17B10
SCHEMBL4111276 0.86 CYP19A1 (0.68) CYP19A1ARSHBGLMNAHSD17B10
SCHEMBL9420189 0.86 CYP19A1 (0.68) CYP19A1ARSHBGLMNAHSD17B10
SCHEMBL4111278 0.86 CYP19A1 (0.68) CYP19A1ARSHBGLMNAHSD17B10
SCHEMBL13752956 0.86 CYP19A1 (0.68) CYP19A1ARSHBGLMNAHSD17B10
SCHEMBL527919 0.86 CYP19A1 (0.68) CYP19A1ARSHBGLMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114728013-A Methods of treating prolonged pregnancy and complications of menstruation or pregnancy 斯坦福大学托管董事会 2022-07-08 CN claimed
WO-2009152269-A2 METHODS OF QUANTIFYING BIOMARKERS HEALTH RESEARCH, INC. (US) 2009-12-17 WO claimed
US-7495107-B2 Method for manufacturing isoxazole derivative or dihydroisoxazole derivative RIKKYO GAKUIN (JP) 2009-02-24 US claimed
US-20060247288-A1 Method for manufacturing isoxazole derivative or dihydroisoxazole derivative GAKUIN, RIKKYO (JP) 2006-11-02 US claimed
EP-4585211-A2 PULLULAN CAPSULES Capsugel Belgium NV (BE) 2025-07-16 EP disclosed
EP-3609476-B1 PULLULAN CAPSULES CAPSUGEL BELGIUM NV (BE) 2025-06-04 EP disclosed
US-11975107-B2 Compositions and resulting hard capsules comprising hydrophilic coloring foodstuff concentrates CAPSUGEL BELGIUM NV (BE) 2024-05-07 US disclosed
US-11878079-B2 Pullulan capsules CAPSUGEL BELGIUM NV (BE) 2024-01-23 US disclosed
WO-2023094689-A1 COMPOSITIONS FOR PREVENTING OR TREATING SKIN AGING ESTETRA SRL (BE) 2023-06-01 WO disclosed
WO-2023094690-A1 COMPOSITIONS FOR PROMOTING HAIR GROWTH ESTETRA SRL (BE) 2023-06-01 WO disclosed
US-20230131084-A1 PULLULAN CAPSULES CAPSUGEL BELGIUM NV (BE) 2023-04-27 US disclosed
US-11576870-B2 Pullulan capsules CAPSUGEL BELGIUM NV (BE) 2023-02-14 US disclosed
EP-1196179-A2 HYALURONIC ACID DERIVATIVES FOR THE PREVENTION AND TREATMENT OF CUTANEOUS SCARS FIDIA ADVANCED BIOPOLYMERS S.R.L. (IT) 2002-04-17 EP disclosed
US-6274118-B1 INJECTING PATIENT HAVING ENDOCRINE CANCER IN NON-PROSTATIC TISSUE WITH BIOLOGICAL BINDING UNITS WHICH BIND TO PROSTATE SPECIFIC ANTIGEN PRODUCED BY NON-PROSTATIC TISSUE NORDION INTERNATIONAL INC. (CA) 2001-08-14 US disclosed
WO-2001000190-A2 HYALURONIC ACID DERIVATIVES FOR THE PREVENTION AND TREATMENT OF CUTANEOUS SCARS FIDIA ADVANCED BIOPOLYMERS, S.R.L. (IT) 2001-01-04 WO disclosed
EP-1027057-A1 TREATMENT OF FEMALE SEXUAL DYSFUNCTION Asivi, LLC (US) 2000-08-16 EP disclosed
WO-1999021562-A1 TREATMENT OF FEMALE SEXUAL DYSFUNCTION ASIVI, LLC (US) 1999-05-06 WO disclosed
WO-1995002424-A1 LOCALIZATION AND THERAPY OF NON-PROSTATIC ENDOCRINE CANCER WITH AGENTS DIRECTED AGAINST PROSTATE SPECIFIC ANTIGEN NORDION INTERNATIONAL INC. (CA) 1995-01-26 WO disclosed
EP-0053845-A1 17-Beta-ethynylsteroids and process for preparing same MITSUBISHI KASEI CORPORATION (JP) 1982-06-16 EP disclosed
US-4115563-A Pharmaceutical steroid formulation STERLING DRUG INC. (US) 1978-09-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060247288-A1 Method for manufacturing isoxazole derivative or dihydroisoxazole derivative CYP3A7, NDUFS7, IDH3A CYP19A1 329/4885AR 2343/4885SHBG 4797/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.