Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 1/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 5/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP4B1 | P13584 | 2/20 | 0.37 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.37 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.37 |
| ▸ | CYP2A7 | P20853 | 2/20 | 0.37 |
| ▸ | CYP3A7 | P24462 | 2/20 | 0.37 |
| ▸ | CYP2F1 | P24903 | 2/20 | 0.37 |
| ▸ | CYP2C18 | P33260 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP2J2 | P51589 | 2/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25546332 | 0.92 | FBP1 (0.41) | FBP1CYP1A1CYP1B1CYP1A2CYP2E1 | |
| SCHEMBL25546318 | 0.88 | FBP1 (0.38) | FBP1ADORA2AADORA1KMT2AMEN1 | |
| SCHEMBL25545933 | 0.87 | TDP1 (0.44) | FBP1ADORA2AADORA1SMN1; SMN2KDM4E | |
| SCHEMBL25556546 | 0.84 | FBP1 (0.42) | FBP1CYP1A1CYP1B1CYP1A2CYP2E1 | |
| SCHEMBL25545941 | 0.80 | LMNA (0.48) | FBP1KMT2AMEN1SMN1; SMN2KDM4E | |
| SCHEMBL25545928 | 0.79 | FBP1 (0.42) | FBP1KMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL25546362 | 0.79 | FBP1 (0.42) | FBP1KMT2AMEN1 | |
| SCHEMBL25545932 | 0.79 | FBP1 (0.44) | FBP1KDM4EALDH1A1TDP1LMNA | |
| SCHEMBL25546361 | 0.78 | FBP1 (0.43) | FBP1KMT2AMEN1LMNAMAPT | |
| SCHEMBL25546325 | 0.78 | S1PR1 (0.50) | FBP1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230150997-A1 | EIF4E INHIBITORS AND USES THEREOF | PIC Therapeutics, Inc. | 2023-05-18 | — | — | US | disclosed |
| US-20230150997-A1 | EIF4E INHIBITORS AND USES THEREOF | PIC Therapeutics, Inc. | 2023-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230150997-A1 | EIF4E INHIBITORS AND USES THEREOF | EIF4E, EIF4EBP1, EIF4A1 | FBP1 735/4885CYP1A1 4849/4885CYP1B1 4728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.