Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL22284403 | 0.99 | GPR119 (0.32) | GPR119 | |
| SCHEMBL22311083 | 0.86 | GPR119 (0.40) | GPR119 | |
| SCHEMBL22284325 | 0.83 | ITGB3 (0.39) | GPR119 | |
| SCHEMBL22284269 | 0.82 | GPR119 (0.55) | GPR119 | |
| SCHEMBL20068581 | 0.81 | THRB (0.40) | GPR119 | |
| Hydrochloric Acid SCHEMBL30451608 | 0.80 | THRB (0.39) | GPR119 | |
| Hydrochloric Acid SCHEMBL22284419 | 0.80 | THRB (0.39) | GPR119 | |
| Hydrochloric Acid SCHEMBL22284417 | 0.80 | THRB (0.39) | GPR119 | |
| SCHEMBL20068598 | 0.80 | ITGB3 (0.43) | GPR119 | |
| SCHEMBL22311417 | 0.79 | GPR119 (0.38) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11655216-B2 | Aryl and heteroaryl ether derivatives as liver X receptor beta agonists, compositions, and their use | MERCK SHARP & DOHME LLC (US) | 2023-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11655216-B2 | Aryl and heteroaryl ether derivatives as liver X receptor beta agonists, compositions, and their use | NR1H2, NR1H3, NR1H4 | GPR119 15/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.