Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | XDH | P47989 | 4/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 2/20 | 0.39 |
| ▸ | SRC | P12931 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 4/20 | 0.38 |
| ▸ | PLAU | P00749 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | P4HB | P07237 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2908238 | 0.86 | KDM4E (0.75) | KDM4EALDH1A1LMNAHPGDXDH | |
| SCHEMBL30097953 | 0.80 | KDM4E (0.48) | KDM4EALDH1A1LMNAHPGDXDH | |
| SCHEMBL25547763 | 0.80 | KDM4E (0.48) | KDM4EALDH1A1LMNAHPGDXDH | |
| SCHEMBL25547290 | 0.79 | KDM4E (0.43) | KDM4EALDH1A1LMNAHPGDPLAU | |
| SCHEMBL14360690 | 0.78 | KDM4E (0.58) | KDM4EALDH1A1LMNAHPGDXDH | |
| SCHEMBL30503469 | 0.74 | KDM4E (0.75) | KDM4EALDH1A1LMNAHPGDGAA | |
| SCHEMBL28941241 | 0.74 | KDM4E (0.75) | KDM4EALDH1A1LMNAHPGDGAA | |
| SCHEMBL1771123 | 0.73 | HPGD (1.00) | KDM4EALDH1A1LMNAHPGDPOLB | |
| SCHEMBL12596874 | 0.73 | KDM4E (0.77) | KDM4EALDH1A1LMNAHPGDXDH | |
| SCHEMBL12848655 | 0.72 | ALDH1A1 (0.71) | KDM4EALDH1A1LMNAHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230149558-A1 | DUOCARMYCIN DERIVATIVE AND USE THEREOF | THE UNIVERSITY OF TOKYO (JP) | 2023-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230149558-A1 | DUOCARMYCIN DERIVATIVE AND USE THEREOF | MRPS18A, MRM1, MRPS17 | KDM4E 2981/4885ALDH1A1 3034/4885LMNA 30/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.