SCHEMBL25548221

SCHEMBL25548221

c1ccc(-c2ccccc2-c2nc(-c3ccc4sc5ccccc5c4c3)nc(-c3ccc4ccc5ccc6nn(-c7ccccc7)nc6c5c4c3)n2)cc1

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.35
ABCG2 Q9UNQ0 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25548219 0.93 ALOX5 (0.34) ALOX5ABCG2
SCHEMBL25548216 0.92 ALOX5 (0.37) ALOX5ABCG2
SCHEMBL26476041 0.92 ALOX5 (0.33) ALOX5ABCG2
SCHEMBL25548227 0.91 ALOX5 (0.34) ALOX5ABCG2
SCHEMBL25548224 0.91 ALOX5 (0.36) ALOX5
SCHEMBL25548226 0.91 ALOX5 (0.36) ALOX5
SCHEMBL25548185 0.89 ABCG2 (0.40) ALOX5ABCG2
SCHEMBL25548244 0.89 ALOX5 (0.35) ALOX5
SCHEMBL25548245 0.89 ALOX5 (0.37) ALOX5ABCG2
SCHEMBL25548645 0.88 ALOX5 (0.36) ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230167089-A1 ORGANIC MATERIAL COMPOSITION AND APPLICATIONS THEREOF NINGBO LUMILAN ADVANCED MATERIALS CO., LTD. (CN) 2023-06-01 US disclosed
US-20230167089-A1 ORGANIC MATERIAL COMPOSITION AND APPLICATIONS THEREOF NINGBO LUMILAN ADVANCED MATERIALS CO., LTD. (CN) 2023-06-01 US disclosed
US-20230157161-A1 ORGANIC MATERIAL COMPOSITION AND APPLICATIONS THEREOF NINGBO LUMILAN ADVANCED MATERIALS CO., LTD. (CN) 2023-05-18 US disclosed
US-20230157161-A1 ORGANIC MATERIAL COMPOSITION AND APPLICATIONS THEREOF NINGBO LUMILAN ADVANCED MATERIALS CO., LTD. (CN) 2023-05-18 US disclosed
US-20230134923-A1 ORGANIC MATERIAL COMPOSITION AND APPLICATIONS THEREOF NINGBO LUMILAN ADVANCED MATERIALS CO., LTD. (CN) 2023-05-04 US disclosed
US-20230134923-A1 ORGANIC MATERIAL COMPOSITION AND APPLICATIONS THEREOF NINGBO LUMILAN ADVANCED MATERIALS CO., LTD. (CN) 2023-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230167089-A1 ORGANIC MATERIAL COMPOSITION AND APPLICATIONS THEREOF PIEZO1, VCL, VDAC3 ALOX5 977/4885ABCG2 739/4885
US-20230134923-A1 ORGANIC MATERIAL COMPOSITION AND APPLICATIONS THEREOF PIEZO1, VCL, VDAC3 ALOX5 977/4885ABCG2 739/4885
US-20230157161-A1 ORGANIC MATERIAL COMPOSITION AND APPLICATIONS THEREOF PIEZO1, VCL, VDAC3 ALOX5 977/4885ABCG2 739/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.