Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.46 |
| ▸ | ERN1 | O75460 | 2/20 | 0.43 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15332229 | 0.87 | KDM4E (0.58) | KDM4ERAB9APTGDR2ERN1TUBB1 | |
| SCHEMBL271557 | 0.83 | LMNA (0.51) | KDM4ERAB9AERN1TUBB1LMNA | |
| SCHEMBL5883150 | 0.83 | PTGDR2 (0.62) | KDM4ERAB9APTGDR2ERN1TUBB1 | |
| SCHEMBL5882953 | 0.82 | ALDH1A1 (0.60) | KDM4ERAB9APTGDR2ERN1TUBB1 | |
| SCHEMBL2556226 | 0.81 | PTGDR2 (0.49) | KDM4ERAB9APTGDR2ERN1LMNA | |
| SCHEMBL2556401 | 0.80 | PTGDR2 (0.70) | KDM4ERAB9APTGDR2ERN1ALDH1A1 | |
| SCHEMBL2560137 | 0.78 | ERN1 (0.45) | KDM4ERAB9AERN1LMNAALDH1A1 | |
| SCHEMBL15330205 | 0.78 | PTGDR2 (0.49) | KDM4EPTGDR2ERN1LMNAALDH1A1 | |
| SCHEMBL24765223 | 0.77 | TUBB1 (0.64) | KDM4ERAB9AERN1TUBB1LMNA | |
| SCHEMBL29965788 | 0.77 | TUBB1 (0.64) | KDM4ERAB9AERN1TUBB1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2558577-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2013-02-20 | — | — | EP | disclosed |
| WO-2011127933-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2011-10-20 | — | — | WO | disclosed |