Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12515401 | 0.88 | KMT2A (0.38) | SLC18A3ALDH1A1MAPTLMNAMAPK1 | |
| SCHEMBL255526 | 0.82 | P2RY14 (0.39) | SLC18A3ALDH1A1MAPTLMNAPOLB | |
| SCHEMBL255525 | 0.78 | MAPT (0.53) | ALDH1A1MAPTLMNAMAPK1KDM4E | |
| SCHEMBL255529 | 0.77 | ALDH1A1 (0.48) | SLC18A3ALDH1A1MAPTLMNAMAPK1 | |
| SCHEMBL4868568 | 0.71 | KMT2A (0.37) | ALDH1A1MAPTLMNAMAPK1GAA | |
| SCHEMBL12515918 | 0.70 | ABCC8 (0.36) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL12515974 | 0.69 | ALDH1A1 (0.38) | ALDH1A1MAPTLMNAMAPK1POLB | |
| SCHEMBL12515981 | 0.69 | KMT2A (0.45) | ALDH1A1MAPTLMNAMAPK1GAA | |
| SCHEMBL255558 | 0.67 | SLC6A2 (0.50) | ALDH1A1MAPTLMNAMAPK1MEN1 | |
| SCHEMBL12515344 | 0.66 | SLC18A3 (0.31) | SLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012029032-A2 | HETEROCYCLIC COMPOUNDS AS DGAT1 INHIBITORS | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2012-03-08 | — | — | WO | disclosed |