Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.64 |
| ▸ | TRAP1 | Q12931 | 4/20 | 0.64 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.56 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 14/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 11/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20118840 | 0.86 | HSP90AA1 (0.63) | HSP90AA1TRAP1HSP90AB1HSP90B1ADORA2A | |
| SCHEMBL23388290 | 0.84 | HSP90AA1 (0.57) | HSP90AA1TRAP1HSP90AB1HSP90B1ADORA2A | |
| SCHEMBL3394461 | 0.84 | TRAP1 (0.67) | HSP90AA1TRAP1HSP90AB1HSP90B1ADORA2A | |
| SCHEMBL20118865 | 0.83 | HSP90AA1 (0.68) | HSP90AA1TRAP1HSP90AB1HSP90B1ADORA2A | |
| SCHEMBL25546964 | 0.83 | HSP90AA1 (0.66) | HSP90AA1TRAP1HSP90AB1HSP90B1ADORA2A | |
| SCHEMBL20118702 | 0.81 | TRAP1 (0.65) | HSP90AA1TRAP1HSP90AB1HSP90B1ADORA2A | |
| SCHEMBL29031963 | 0.81 | ADORA2A (0.49) | HSP90AA1TRAP1ADORA2AADORA1ADORA3 | |
| SCHEMBL20118740 | 0.81 | TRAP1 (0.64) | HSP90AA1TRAP1HSP90AB1HSP90B1ADORA2A | |
| SCHEMBL20118691 | 0.80 | HSP90AA1 (0.62) | HSP90AA1TRAP1HSP90AB1HSP90B1ADORA2A | |
| SCHEMBL20118614 | 0.80 | HSP90AA1 (0.60) | HSP90AA1TRAP1HSP90AB1HSP90B1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159534-A1 | ADENOSINE RECEPTOR ANTAGONIST COMPOUNDS | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159534-A1 | ADENOSINE RECEPTOR ANTAGONIST COMPOUNDS | ADORA2A, ADORA1, ADORA3 | HSP90AA1 2208/4885TRAP1 1393/4885HSP90AB1 1972/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.