SCHEMBL25549482

SCHEMBL25549482

CCCCCCCCCCCCc1ccc(-c2nc(Cl)nc(-c3ccc([Si](C)(C)C)cc3)n2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.49
MAPT P10636 3/20 0.49
HSD17B10 Q99714 3/20 0.49
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
RAB9A P51151 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
KDM4E B2RXH2 2/20 0.49
USP2 O75604 1/20 0.49
GAA P10253 1/20 0.49
HPGD P15428 1/20 0.49
SPHK1 Q9NYA1 6/20 0.45
RARB P10826 5/20 0.44
RARA P10276 1/20 0.44
MTOR P42345 1/20 0.44
SPHK2 Q9NRA0 5/20 0.43
TSHR P16473 1/20 0.42
NPC1 O15118 1/20 0.42
NFKB1 P19838 1/20 0.42
S1PR1 P21453 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25549475 0.93 ALDH1A1 (0.55) ALDH1A1MAPTHSD17B10MEN1KMT2A
SCHEMBL3621133 0.91 ALDH1A1 (0.56) ALDH1A1MAPTHSD17B10MEN1KMT2A
SCHEMBL12622274 0.83 ALDH1A1 (0.65) ALDH1A1MAPTHSD17B10MEN1KMT2A
SCHEMBL9945516 0.82 RAB9A (0.50) ALDH1A1MAPTHSD17B10MEN1KMT2A
SCHEMBL12622306 0.82 ALDH1A1 (0.63) ALDH1A1MAPTHSD17B10MEN1KMT2A
SCHEMBL5148656 0.82 HSD17B10 (0.59) ALDH1A1MAPTHSD17B10MEN1KMT2A
SCHEMBL13539888 0.82 ALDH1A1 (0.62) ALDH1A1MAPTHSD17B10MEN1KMT2A
SCHEMBL16615370 0.77 ALDH1A1 (0.58) ALDH1A1MAPTHSD17B10MEN1KMT2A
SCHEMBL11976539 0.77 ALDH1A1 (0.58) ALDH1A1MAPTHSD17B10MEN1KMT2A
SCHEMBL12628223 0.77 HSD11B1 (0.62) ALDH1A1MAPTHSD17B10MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11667835-B2 Light-emitting composition SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2023-06-06 US disclosed