Malonic Acid

Malonic Acid

SCHEMBL2554958

O=C(O)CC(=O)CC(C(=O)O)C(=O)O.O=C(O)CC(=O)O

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.50
SRR Q9GZT4 1/20 0.50
TDP1 Q9NUW8 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.38
SLC22A6 Q4U2R8 1/20 0.35
FOLH1 Q04609 5/20 0.34
RIMKLA Q8IXN7 1/20 0.30
NAALAD2 Q9Y3Q0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2475950 0.97 LDHA (0.44) LDHASRRTDP1SMN1; SMN2SLC22A6
SCHEMBL27782115 0.78 TDP1 (0.42) TDP1SMN1; SMN2SLC22A6
SCHEMBL11762118 0.77 LDHA (0.47) LDHASRRTDP1SMN1; SMN2SLC22A6
SCHEMBL9005314 0.76 SMN1; SMN2 (0.62) LDHASRRTDP1SMN1; SMN2SLC22A6
SCHEMBL4669647 0.76 SMN1; SMN2 (0.62) LDHASRRTDP1SMN1; SMN2SLC22A6
SCHEMBL2491511 0.74 GRIK1 (0.48)
SCHEMBL17733 0.72 ALDH1A1 (0.46) LDHASRRTDP1SLC22A6
SCHEMBL16937252 0.72 LDHA (0.42) LDHASRRTDP1SMN1; SMN2SLC22A6
SCHEMBL786963 0.72 CA2 (0.46) LDHASRRTDP1FOLH1
SCHEMBL110197 0.72 TDP1 (0.59) LDHASRRTDP1SMN1; SMN2SLC22A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2556106-A1 CROSSLINKABLE COMPOSITION CROSSLINKABLE WITH A LATENT BASE CATALYST Nuplex Resins B.V. (NL) 2013-02-13 EP disclosed
WO-2011124664-A1 CROSSLINKABLE COMPOSITION CROSSLINKABLE WITH A LATENT BASE CATALYST NUPLEX RESINS B.V. (NL) 2011-10-13 WO disclosed