Sugi Predict

Sugi Predict / Compounds / SCHEMBL2555043

SCHEMBL2555043

SCHEMBL2555043

Nc1ccccc1C(=O)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 2/20 0.59
▸ GAA P10253 1/20 0.59
▸ ALDH1A1 P00352 9/20 0.52
▸ HSD17B10 Q99714 9/20 0.52
▸ CFTR P13569 1/20 0.52
▸ KDM4E B2RXH2 5/20 0.48
▸ MMP2 P08253 1/20 0.48
▸ POLB P06746 2/20 0.47
▸ CYP2C19 P33261 1/20 0.47
▸ ALOX15 P16050 2/20 0.46
▸ NPC1 O15118 3/20 0.46
▸ RAB9A P51151 3/20 0.46
▸ TSHR P16473 3/20 0.46
▸ HPGD P15428 2/20 0.46
▸ SMN1; SMN2 Q16637 2/20 0.46
▸ TP53 P04637 2/20 0.46
▸ GLA P06280 1/20 0.46
▸ CYP3A4 P08684 1/20 0.46
▸ MAPK1 P28482 1/20 0.46
▸ HIF1A Q16665 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29723321 1.00 MAPT (0.59) MAPTGAAALDH1A1HSD17B10CFTR
SCHEMBL1885621 0.87 MAPT (0.60) MAPTGAAALDH1A1HSD17B10CFTR
SCHEMBL6691083 0.82 MAPT (0.67) MAPTGAAALDH1A1HSD17B10CFTR
SCHEMBL1645158 0.82 ALDH1A1 (0.58) MAPTALDH1A1KDM4EPOLBCYP2C19
Benzil SCHEMBL3796381 0.80 MAPT (0.64) MAPTGAAALDH1A1HSD17B10CFTR
Anthranilic Acid SCHEMBL675 0.80 ALDH1A1 (0.65) MAPTGAAALDH1A1HSD17B10CFTR
Anthranilic Acid SCHEMBL362171 0.80 ALDH1A1 (0.65) MAPTGAAALDH1A1HSD17B10CFTR
Anthranilic Acid SCHEMBL2953168 0.80 ALDH1A1 (0.65) MAPTGAAALDH1A1HSD17B10CFTR
Anthranilic Acid SCHEMBL2961107 0.80 ALDH1A1 (0.65) MAPTGAAALDH1A1HSD17B10CFTR
Anthranilic Acid SCHEMBL3110791 0.80 ALDH1A1 (0.65) MAPTGAAALDH1A1HSD17B10CFTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111995569-B Preparation method of cyclin-dependent kinase inhibitor intermediate 成都博腾药业有限公司 2023-12-05 — — CN claimed
CN-114716685-B Polycarboxylic acid dispersant, preparation method thereof, polycarboxylic acid dispersant and application 上海安诺其集团股份有限公司 2023-03-14 — — CN claimed
CN-111995569-A Preparation method of cyclin-dependent kinase inhibitor intermediate 成都博腾药业有限公司 2020-11-27 — — CN claimed
CN-103788941-B A kind of novel mercapto fluorescence probe, preparation method and application thereof CHINA PHARMACEUTICAL UNIVERSITY (CN) 2016-01-20 — — CN claimed
WO-2011124227-A1 BIOCIDAL ACID-ADJUSTED POLYMER WITH POLYPROPYLENE VESTERGAARD FRANDSEN SA (CH) 2011-10-13 — — WO claimed
WO-2011124228-A1 A BIOCIDAL POLYOLEFIN YARN WITH 3-12 FILAMENTS VESTERGAARD FRANDSEN SA (CH) 2011-10-13 — — WO claimed
EP-1705227-A2 New dyestuffs and colorants with specific carbonyl compounds Henkel Kommanditgesellschaft auf Aktien (DE) 2006-09-27 — — EP claimed
US-4267333-A Preparation of 2-trifluoromethyl cinchoninic acids UNION CARBIDE AGRICULTURAL PRODUCTS COMPANY, INC. (US) 1981-05-12 — — US claimed
US-4251661-A Preparation of 2-trifluoromethyl cinchoninic acids UNION CARBIDE CORPORATION (US) 1981-02-17 — — US claimed
CN-111995569-B Preparation method of cyclin-dependent kinase inhibitor intermediate 成都博腾药业有限公司 2023-12-05 — — CN disclosed
CN-114716685-B Polycarboxylic acid dispersant, preparation method thereof, polycarboxylic acid dispersant and application 上海安诺其集团股份有限公司 2023-03-14 — — CN disclosed
CN-111995569-A Preparation method of cyclin-dependent kinase inhibitor intermediate 成都博腾药业有限公司 2020-11-27 — — CN disclosed
US-10287601-B2 Indole-derived compound production BOARD OF TRUSTEES OF SOUTHERN ILLINOIS UNIVERSITY (US) 2019-05-14 — — US disclosed
CN-108610286-A A kind of 2- aryl-4-quinolones derivative and its preparation method and application 绍兴文理学院 2018-10-02 — — CN disclosed
WO-1995006039-A1 NOVEL PHENYL GLYOXYLIC ACID DERIVATIVES, PROCESSES FOR PRODUCING THEM AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS HOECHST SCHERING AGREVO GMBH (DE) 1995-03-02 — — WO disclosed
US-4639454-A LYMPHOID LEUKEMIA E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-01-27 — — US disclosed
US-4267333-A Preparation of 2-trifluoromethyl cinchoninic acids UNION CARBIDE AGRICULTURAL PRODUCTS COMPANY, INC. (US) 1981-05-12 — — US disclosed
US-4267333-A Preparation of 2-trifluoromethyl cinchoninic acids UNION CARBIDE AGRICULTURAL PRODUCTS COMPANY, INC. (US) 1981-05-12 — — US disclosed
US-4251661-A Preparation of 2-trifluoromethyl cinchoninic acids UNION CARBIDE CORPORATION (US) 1981-02-17 — — US disclosed
US-4251661-A Preparation of 2-trifluoromethyl cinchoninic acids UNION CARBIDE CORPORATION (US) 1981-02-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10287601-B2 Indole-derived compound production INMT, IDO1, IDO2 MAPT 1329/4885GAA 2254/4885ALDH1A1 303/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.