SCHEMBL6691083

SCHEMBL6691083

Nc1ccccc1C(=O)C(=O)c1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.67
GAA P10253 1/20 0.67
CES2 O00748 7/20 0.61
CES1 P23141 6/20 0.61
HSD17B10 Q99714 3/20 0.48
ALDH1A1 P00352 2/20 0.48
CFTR P13569 1/20 0.48
POLB P06746 2/20 0.47
KDM4E B2RXH2 2/20 0.46
HDAC3 O15379 1/20 0.46
MAPK1 P28482 1/20 0.46
HDAC1 Q13547 1/20 0.46
HDAC2 Q92769 1/20 0.46
MMP2 P08253 1/20 0.45
KMT2A Q03164 1/20 0.45
CYP3A4 P08684 1/20 0.44
PARP1 P09874 1/20 0.44
TSHR P16473 1/20 0.44
CYP2C19 P33261 1/20 0.44
RECQL P46063 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzil SCHEMBL3796381 0.98 MAPT (0.64) MAPTGAACES2CES1HSD17B10
SCHEMBL2877065 0.92 MAPT (0.58) MAPTGAACES2CES1HSD17B10
SCHEMBL1885621 0.89 MAPT (0.60) MAPTGAACES2CES1HSD17B10
Methacrylic Acid SCHEMBL8010054 0.88 MAPT (0.53) MAPTGAACES2CES1HSD17B10
SCHEMBL1885623 0.86 MAPT (0.55) MAPTGAACES2CES1HSD17B10
SCHEMBL28110230 0.84 MAPT (0.53) MAPTGAACES2CES1HSD17B10
SCHEMBL8395171 0.84 MMP2 (0.63) MAPTGAACES2CES1HSD17B10
SCHEMBL22890837 0.84 MAPT (0.58) MAPTGAACES2CES1HSD17B10
Hydrochloric Acid SCHEMBL27739689 0.84 MAPT (0.53) MAPTGAACES2CES1HSD17B10
SCHEMBL8574337 0.84 CES2 (0.78) MAPTGAACES2CES1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116903817-A High-performance transparent polyurea film based on dual dynamic non-covalent effect and preparation and application thereof 华南理工大学 2023-10-20 CN claimed
US-20120316092-A1 LUBRICANT COMPOSITION FOR CONTINUOUSLY VARIABLE TRANSMISSION JATCO LTD. (JP) 2012-12-13 US claimed
WO-1998024111-A1 A SOLUTION FOR MAKING PHOTOCONDUCTIVE LAYERS AND THEIR ELECTROPHOTOGRAPHICAL MANUFACTURING IN CRTS ORION ELECTRIC CO., LTD. (KR) 1998-06-04 WO claimed
US-20250339405-A1 a-SYNUCLEIN AGGREGATE BINDING AGENT AND IMAGING METHOD NATIONAL INSTITUTES FOR QUANTUM AND RADIOLOGICAL SCIENCE AND TECH (JP) 2025-11-06 US disclosed
CN-117865847-A Ligand compound containing benzidine group, metal complex, metal supported catalyst and application thereof 合肥中科科乐新材料有限责任公司 2024-04-12 CN disclosed
CN-117865847-A Ligand compound containing benzidine group, metal complex, metal supported catalyst and application thereof 合肥中科科乐新材料有限责任公司 2024-04-12 CN disclosed
US-20220133698-A1 a-SYNUCLEIN AGGREGATE BINDING AGENT AND IMAGING METHOD NATIONAL INSTITUTES FOR QUANTUM AND RADIOLOGICAL SCIENCE AND TECHNOLOGY (JP) 2022-05-05 US disclosed
EP-3932405-A1 alpha-SYNUCLEIN AGGREGATE BINDING AGENT AND IMAGING METHOD NATIONAL INSTITUTES FOR QUANTUM AND RADIOLOGICAL SCIENCE AND TECHNOLOGY (JP) 2022-01-05 EP disclosed
CN-106488938-B UV resistant absorbent polyurethane urea resin composition, the formed body and coating material for having used the composition 东曹株式会社 2019-05-10 CN disclosed
CN-106488938-A UV resistant absorbent polyurethane urea resin compositionss, the formed body employing said composition and coating material 东曹株式会社 2017-03-08 CN disclosed
US-9293713-B2 Arylamine compound RICOH COMPANY, LTD. (JP) 2016-03-22 US disclosed
CN-1310360-A Originals for lithographic printing plate FUJI PHOTO FILM CO LTD (JP) 2001-08-29 CN disclosed
US-6090509-A Solution for making photoconductive layers and their electrophotographical manufacturing in CRTs ORION ELECTRIC CO., LTD. (KR) 2000-07-18 US disclosed
US-6090509-A Solution for making photoconductive layers and their electrophotographical manufacturing in CRTs ORION ELECTRIC CO., LTD. (KR) 2000-07-18 US disclosed
WO-1998024111-A1 A SOLUTION FOR MAKING PHOTOCONDUCTIVE LAYERS AND THEIR ELECTROPHOTOGRAPHICAL MANUFACTURING IN CRTS ORION ELECTRIC CO., LTD. (KR) 1998-06-04 WO disclosed
WO-1998024111-A1 A SOLUTION FOR MAKING PHOTOCONDUCTIVE LAYERS AND THEIR ELECTROPHOTOGRAPHICAL MANUFACTURING IN CRTS ORION ELECTRIC CO., LTD. (KR) 1998-06-04 WO disclosed
EP-0052645-B1 GAMMA-EMITTING RECEPTOR-BINDING QUINUCLIDINYL BENZILATES METHODS OF PREPARATION THEREOF AND IMAGING AND ASSAY METHODS UTILIZING SAME Research Corporation (US) 1987-05-13 EP disclosed
EP-0052645-A4 GAMMA-EMITTING RECEPTOR-BINDING QUINUCLIDINYL BENZILATES METHODS OF PREPARATION THEREOF AND IMAGING AND ASSAY METHODS UTILIZING SAME. RESEARCH CORP (US) 1983-03-29 EP disclosed
EP-0052645-A1 GAMMA-EMITTING RECEPTOR-BINDING QUINUCLIDINYL BENZILATES METHODS OF PREPARATION THEREOF AND IMAGING AND ASSAY METHODS UTILIZING SAME. RESEARCH CORP (US) 1982-06-02 EP disclosed
WO-1981003422-A1 GAMMA-EMITTING RECEPTOR-BINDING QUINUCLIDINYL BENZILATES;METHODS OF PREPARATION THEREOF AND IMAGING AND ASSAY METHODS UTILIZING SAME RESEARCH CORP (US) 1981-12-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220133698-A1 a-SYNUCLEIN AGGREGATE BINDING AGENT AND IMAGING METHOD SNCA, HTT, PARK7 MAPT 187/4885GAA 1576/4885CES2 4110/4885
US-20250339405-A1 a-SYNUCLEIN AGGREGATE BINDING AGENT AND IMAGING METHOD SNCA, HTT, PARK7 MAPT 187/4885GAA 1576/4885CES2 4110/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.