SCHEMBL25552148

SCHEMBL25552148

CNC(=O)/C(=N/OC)c1cccc(C)c1CO/N=C(/c1ccc(-c2ccccc2)cc1)C(F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.33
KMT2A Q03164 2/20 0.33
MEN1 O00255 1/20 0.33
HIF1A Q16665 4/20 0.33
S1PR1 P21453 3/20 0.32
MAPT P10636 3/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
MAPK1 P28482 1/20 0.32
HDAC1 Q13547 2/20 0.31
HDAC2 Q92769 2/20 0.31
RAB9A P51151 2/20 0.31
NPC1 O15118 1/20 0.31
CTDSP1 Q9GZU7 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
GAA P10253 1/20 0.30
HDAC3 O15379 1/20 0.30
HDAC4 P56524 1/20 0.30
HDAC7 Q8WUI4 1/20 0.30
HDAC10 Q969S8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23971886 0.94 HIF1A (0.35) KMT2AHIF1ARAB9ANPC1SMN1; SMN2
SCHEMBL25558940 0.94 KMT2A (0.34) POLBKMT2AMEN1HIF1AS1PR1
SCHEMBL25552150 0.91 HIF1A (0.41) POLBKMT2AMEN1HIF1AS1PR1
SCHEMBL25600173 0.88 HIF1A (0.34) KMT2AHIF1ARAB9ANPC1SMN1; SMN2
SCHEMBL23972056 0.87 S1PR1 (0.44) POLBKMT2AMEN1HIF1AS1PR1
SCHEMBL23971918 0.85 HIF1A (0.44) KMT2AHIF1ARAB9ANPC1SMN1; SMN2
SCHEMBL25552168 0.84 HIF1A (0.38) POLBKMT2AMEN1HIF1AS1PR1
SCHEMBL23971873 0.83 HIF1A (0.40) HIF1AS1PR1RAB9ANPC1
SCHEMBL23971827 0.82 HIF1A (0.34) KMT2AMEN1HIF1AALDH1A1RAB9A
SCHEMBL23971751 0.82 S1PR1 (0.41) HIF1AS1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230172205-A1 USE OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS IV BASF SE (DE) 2023-06-08 US disclosed
US-20230172205-A1 USE OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS IV BASF SE (DE) 2023-06-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230172205-A1 USE OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS IV COX5B, SQOR, COX5A POLB 341/4885KMT2A 3828/4885MEN1 2840/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.