Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 3/20 | 0.39 |
| ▸ | GRM7 | Q14831 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | UGT2B17 | O75795 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23873502 | 0.80 | CHRNB2 (0.43) | CHRNB2CHRNA4TP53TDP1MGLL | |
| SCHEMBL15567031 | 0.79 | CHRNB2 (0.44) | CHRNB2CHRNA4TP53TDP1GRM7 | |
| SCHEMBL25026055 | 0.78 | CHRNB2 (0.47) | CHRNB2CHRNA4HTR2AHTR2CHTR2B | |
| SCHEMBL25025538 | 0.78 | CHRNB2 (0.47) | CHRNB2CHRNA4HTR2AHTR2CHTR2B | |
| SCHEMBL30234302 | 0.78 | CHRNB2 (0.47) | CHRNB2CHRNA4HTR2AHTR2CHTR2B | |
| SCHEMBL23908052 | 0.77 | CHRNB2 (0.41) | CHRNB2CHRNA4TP53TDP1MGLL | |
| SCHEMBL29936479 | 0.77 | CHRNB2 (0.41) | CHRNB2CHRNA4TP53TDP1MGLL | |
| SCHEMBL11295388 | 0.75 | PSMB5 (0.45) | CHRNB2CHRNA4TP53TDP1GRM7 | |
| SCHEMBL31389703 | 0.75 | HTR2C (0.52) | MGLLHTR2AHTR2CHTR2B | |
| SCHEMBL1128140 | 0.73 | PSMB5 (0.47) | CHRNB2CHRNA4GRM7KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230167057-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | NOVARTIS PHARMA AG (CH) | 2023-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230167057-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | STING1, CGAS, IRF3 | CHRNB2 1729/4885CHRNA4 2763/4885TP53 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.