Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 6/20 | 0.52 |
| ▸ | HTR2A | P28223 | 3/20 | 0.43 |
| ▸ | HTR2B | P41595 | 3/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17304002 | 0.81 | CHRNB4 (0.55) | HTR2CKDM1A | |
| SCHEMBL31389967 | 0.77 | CHRNB4 (0.43) | HTR2C | |
| SCHEMBL1225741 | 0.77 | HTR2C (0.72) | HTR2CHTR2AHTR2BOPRL1KCNH2 | |
| SCHEMBL23873437 | 0.75 | HTR2C (0.48) | HTR2CHTR2AHTR2BSLC6A2SLC6A4 | |
| SCHEMBL25554156 | 0.75 | CHRNB2 (0.43) | HTR2CHTR2AHTR2BMGLL | |
| Hydrogen Peroxide SCHEMBL9938282 | 0.74 | HTR2C (0.62) | HTR2COPRL1KCNH2 | |
| SCHEMBL28217704 | 0.74 | KDM1A (0.48) | HTR2CHTR2AHTR2BHRH3SLC6A2 | |
| SCHEMBL31389850 | 0.74 | KDM1A (0.50) | HTR2CHTR2BKDM1A | |
| SCHEMBL18573855 | 0.74 | TP53 (0.50) | HTR2CHTR2AHTR2BOPRL1HRH3 | |
| SCHEMBL31389942 | 0.74 | HTR2C (0.56) | HTR2CHTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025043225-A2 | DEGRADERS OF CYCLIN-DEPENDENT KINASE 2 | GENENTECH, INC. (US) | 2025-02-27 | — | — | WO | disclosed |