Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.39 |
| ▸ | NSD2 | O96028 | 7/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.37 |
| ▸ | PHGDH | O43175 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | PRKDC | P78527 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30353051 | 1.00 | SCN9A (0.40) | SCN9ACYP11B1CYP19A1CYP11B2NSD2 | |
| SCHEMBL30353086 | 0.93 | CYP11B1 (0.40) | SCN9ACYP11B1CYP19A1CYP11B2NSD2 | |
| SCHEMBL25554071 | 0.93 | CYP11B1 (0.40) | SCN9ACYP11B1CYP19A1CYP11B2NSD2 | |
| SCHEMBL30353060 | 0.90 | SCN9A (0.41) | SCN9ACYP11B1CYP19A1CYP11B2NSD2 | |
| SCHEMBL25554317 | 0.90 | SCN9A (0.41) | SCN9ACYP11B1CYP19A1CYP11B2NSD2 | |
| SCHEMBL25555971 | 0.89 | SCN9A (0.38) | SCN9ACYP11B1CYP11B2NSD2 | |
| SCHEMBL30353118 | 0.89 | GRM5 (0.37) | CYP11B1CYP19A1CYP11B2NSD2GRM5 | |
| SCHEMBL25554896 | 0.89 | GRM5 (0.37) | CYP11B1CYP19A1CYP11B2NSD2GRM5 | |
| SCHEMBL25555912 | 0.88 | SCN9A (0.41) | SCN9ACYP11B1CYP11B2NSD2PIN1 | |
| SCHEMBL30257252 | 0.87 | NSD2 (0.39) | CYP11B1CYP19A1CYP11B2NSD2GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115996910-A | Aryl or heteroaryl derivatives | 帝人制药株式会社 | 2023-04-21 | — | — | CN | claimed |
| US-20230167073-A1 | ARYL OR HETEROARYL DERIVATIVE | TEIJIN PHARMA LIMITED (JP) | 2023-06-01 | — | — | US | disclosed |
| US-20230167073-A1 | ARYL OR HETEROARYL DERIVATIVE | TEIJIN PHARMA LIMITED (JP) | 2023-06-01 | — | — | US | disclosed |
| CN-115996910-A | Aryl or heteroaryl derivatives | 帝人制药株式会社 | 2023-04-21 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230167073-A1 | ARYL OR HETEROARYL DERIVATIVE | ARRB1, NR3C2, TRPC6 | SCN9A 760/4885CYP11B1 300/4885CYP19A1 3966/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.