Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 7/20 | 0.52 |
| ▸ | MAOB | P27338 | 7/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | CYSLTR1 | Q9Y271 | 7/20 | 0.45 |
| ▸ | CYSLTR2 | Q9NS75 | 6/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | UNG | P13051 | 1/20 | 0.42 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2559956 | 0.85 | SMN1; SMN2 (0.49) | NPC1RAB9ACYSLTR1CYSLTR2SMN1; SMN2 | |
| SCHEMBL9180174 | 0.81 | MAOA (0.59) | MAOAMAOBNPC1RAB9ATDP1 | |
| SCHEMBL2556049 | 0.79 | MRGPRX4 (0.45) | NPC1RAB9ATDP1SMN1; SMN2HTT | |
| SCHEMBL3554869 | 0.76 | RAB9A (0.52) | NPC1RAB9ASMN1; SMN2MEN1LMNA | |
| SCHEMBL9179434 | 0.75 | PPARG (0.55) | MAOAMAOBMAPT | |
| SCHEMBL9178370 | 0.74 | TDP1 (0.62) | MAOAMAOBNPC1RAB9ATDP1 | |
| SCHEMBL2557002 | 0.73 | NPC1 (0.63) | MAOAMAOBNPC1RAB9ACYSLTR1 | |
| SCHEMBL2559248 | 0.73 | MAOA (0.71) | MAOAMAOBRAB9ASMN1; SMN2 | |
| SCHEMBL3052586 | 0.71 | KDM4E (0.63) | NPC1RAB9ACYSLTR1CYSLTR2SMN1; SMN2 | |
| SCHEMBL3052584 | 0.71 | KDM4E (0.63) | NPC1RAB9ACYSLTR1CYSLTR2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |
| EP-2558577-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2013-02-20 | — | — | EP | disclosed |
| WO-2011127933-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2011-10-20 | — | — | WO | disclosed |