Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 7/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | PHGDH | O43175 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22233136 | 0.89 | GSK3B (0.34) | MEN1KMT2ATRPV1GSK3BDYRK1A | |
| Hydrochloric Acid SCHEMBL25205737 | 0.88 | GSK3B (0.34) | MEN1KMT2ATRPV1GSK3BDYRK1A | |
| SCHEMBL22254953 | 0.88 | GSK3B (0.36) | TRPV1GSK3BDYRK1AFAAHATM | |
| SCHEMBL22255230 | 0.88 | TRPV1 (0.34) | MEN1KMT2ATRPV1GSK3BDYRK1A | |
| SCHEMBL25547020 | 0.88 | TRPV1 (0.34) | MEN1KMT2ATRPV1GSK3BDYRK1A | |
| SCHEMBL22233796 | 0.87 | GSK3B (0.35) | MEN1KMT2ATRPV1GSK3BDYRK1A | |
| SCHEMBL22255232 | 0.87 | GSK3B (0.34) | MEN1KMT2ATRPV1GSK3BDYRK1A | |
| SCHEMBL25531588 | 0.87 | GSK3B (0.34) | MEN1KMT2ATRPV1GSK3BDYRK1A | |
| SCHEMBL25556936 | 0.87 | ROCK2 (0.37) | FAAH | |
| Hydrochloric Acid SCHEMBL22233632 | 0.87 | GSK3B (0.34) | MEN1KMT2ATRPV1GSK3BDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159491-A1 | Antimicrobial Compounds and Methods | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159491-A1 | Antimicrobial Compounds and Methods | MPO, NISCH, RPN2 | MEN1 4216/4885KMT2A 4067/4885TRPV1 848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.