Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.54 |
| ▸ | PPARA | Q07869 | 7/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ACACB | O00763 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.47 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.47 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.47 |
| ▸ | ALB | P02768 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | RARB | P10826 | 1/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4666674 | 1.00 | PPARG (0.54) | PPARGPPARASLC6A2SLC6A3TBXAS1 | |
| SCHEMBL4666677 | 1.00 | PPARG (0.54) | PPARGPPARASLC6A2SLC6A3TBXAS1 | |
| SCHEMBL11237591 | 0.89 | TBXAS1 (0.59) | TBXAS1TSHRPTGS1PTGS2LMNA | |
| SCHEMBL27488752 | 0.85 | PPARG (0.49) | PPARGPPARASLC6A2SLC6A3TSHR | |
| SCHEMBL14258111 | 0.84 | TBXAS1 (0.51) | PPARGTBXAS1TSHRPTGS1PTGS2 | |
| SCHEMBL7933439 | 0.84 | TBXAS1 (0.51) | PPARGTBXAS1TSHRPTGS1PTGS2 | |
| SCHEMBL13235901 | 0.84 | SLC6A2 (0.53) | PPARGPPARASLC6A2SLC6A3ACACB | |
| SCHEMBL11145872 | 0.84 | SLC6A2 (0.53) | PPARGPPARASLC6A2SLC6A3ACACB | |
| SCHEMBL11242882 | 0.84 | SLC6A2 (0.53) | PPARGPPARASLC6A2SLC6A3ACACB | |
| SCHEMBL27473580 | 0.84 | PTGS1 (0.56) | TBXAS1TSHRACACBPTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114487184-B | Method for determining 2 beta-methyl ester-3 beta- (4-chlorophenyl) tropane and related substances thereof | 江苏省原子医学研究所 | 2023-09-22 | — | — | CN | claimed |
| CN-114487184-A | Method for measuring 2 beta-carbomethoxy-3 beta- (4-chlorphenyl) tropane and related substances thereof | 江苏省原子医学研究所 | 2022-05-13 | — | — | CN | claimed |
| US-20170115259-A1 | HIGH PERFORMANCE LIQUID CHROMATOGRAPHY METHOD FOR ANALYZING IMAGING AGENT, PRECURSOR OF IMAGING AGENT, OR INTERMEDIATE OF IMAGING AGENT | Institute of Nuclear Energy Research, Atomic Energy Council, Executive Yuan, R.O.C. (TW) | 2017-04-27 | — | — | US | claimed |
| CN-117295825-A | Biomarkers for the treatment of cancer using MDM2 antagonists | 大冢制药株式会社 | 2023-12-26 | — | — | CN | disclosed |
| CN-114487184-B | Method for determining 2 beta-methyl ester-3 beta- (4-chlorophenyl) tropane and related substances thereof | 江苏省原子医学研究所 | 2023-09-22 | — | — | CN | disclosed |
| CN-116194088-A | Biomarkers for the treatment of cancer using MDM2 antagonists | 大冢制药株式会社 | 2023-05-30 | — | — | CN | disclosed |
| US-11638707-B2 | Substituted amino triazoles useful as chitinase inhibitors | MOLECURE S.A. (PL) | 2023-05-02 | — | — | US | disclosed |
| WO-2023287964-A1 | LIGAND-CONTROLLED DIVERGENT DEHYDROGENATIVE REACTIONS OF ALIPHATIC ACIDS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-01-19 | — | — | WO | disclosed |
| CN-115066614-A | Biomarkers for treating cancer using MDM2 antagonists | 大冢制药株式会社 | 2022-09-16 | — | — | CN | disclosed |
| CN-114487184-A | Method for measuring 2 beta-carbomethoxy-3 beta- (4-chlorphenyl) tropane and related substances thereof | 江苏省原子医学研究所 | 2022-05-13 | — | — | CN | disclosed |
| CN-114487184-A | Method for measuring 2 beta-carbomethoxy-3 beta- (4-chlorphenyl) tropane and related substances thereof | 江苏省原子医学研究所 | 2022-05-13 | — | — | CN | disclosed |
| WO-2004058145-A2 | SUBSTITUTED AMIDES | MERCK & CO., INC. (US) | 2004-07-15 | — | — | WO | disclosed |
| WO-2004058735-A2 | LIGANDS OF MELANOCORTIN RECEPTORS AND COMPOSITIONS AND METHODS RELATED THERETO | NEUROCRINE BIOSCIENCES, INC. (US) | 2004-07-15 | — | — | WO | disclosed |
| US-20040058820-A1 | Central nervous system disorders; psychological disorders; antiinflammatory agents; multiple sclerosis | MERCK SHARP & DOHME LLC | 2004-03-25 | — | — | US | disclosed |
| WO-2004004714-A1 | SPIROCYCLIC PIPERIDINES AS MCH1 ANTAGONISTS AND USES THEREOF | H. LUNDBECK A/S (DK) | 2004-01-15 | — | — | WO | disclosed |
| WO-2003077847-A2 | SUBSTITUTED AMIDES | MERCK & CO., INC. (US) | 2003-09-25 | — | — | WO | disclosed |
| US-6365398-B1 | REACTING RACEMIC CARBOXYLIC ACID ESTER WITH RACEMIC ALCOHOL IN PRESENCE OF A CARBOXYL ESTER HYDROLASE | BASF AKTIENGESELLSCHAFT (DE) | 2002-04-02 | — | — | US | disclosed |
| US-6160194-A | Soil decontamination using ferric chelates and peroxide | THE CONNECTICUT AGRICULTURAL EXPERIMENT STATION (US) | 2000-12-12 | — | — | US | disclosed |
| US-5935953-A | TROPANE DERIVATIVES AS INHIBITORS TO REDUCE THE FEEDING OF AND DELAYING THE MATURATION OF THE INSECTS AND PESTS; INHIBITORS OF A PHENYLETHANOLAMINE, E.G.OCTOPAMINE, REUPTAKE TRANSPORTER; PESTICIDES; PESTISTATS; INSECTICIDES | RESEARCH TRIANGLE INSTITUTE (US) | 1999-08-10 | — | — | US | disclosed |
| US-5380848-A | 8-azabicyclo(3.2.1)octanes | RESEARCH TRIANGLE INSTITUTE (US) | 1995-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040058820-A1 | Central nervous system disorders; psychological disorders; antiinflammatory agents; multiple sclerosis | CNR1, CNR2, MAG | PPARG 297/4885PPARA 780/4885SLC6A2 1371/4885 |
| US-11638707-B2 | Substituted amino triazoles useful as chitinase inhibitors | CHIT1, CHIA, CHI3L1 | PPARG 3658/4885PPARA 4350/4885SLC6A2 4809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.