Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 4/20 | 0.37 |
| ▸ | EDNRA | P25101 | 4/20 | 0.37 |
| ▸ | WDR5 | P61964 | 5/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1151001 | 0.81 | ADRA1D (0.40) | SMN1; SMN2CCR2 | |
| SCHEMBL25053095 | 0.79 | EDNRB (0.48) | EDNRBEDNRAWDR5TSHRGLA | |
| SCHEMBL29738016 | 0.78 | CA1 (0.40) | EDNRBEDNRAWDR5TSHRGLA | |
| SCHEMBL2585091 | 0.78 | CA1 (0.40) | EDNRBEDNRAWDR5TSHRGLA | |
| SCHEMBL2552728 | 0.77 | CA2 (0.41) | EDNRBEDNRAWDR5TSHRGLA | |
| SCHEMBL15139967 | 0.77 | SLC6A4 (0.41) | EDNRBEDNRAWDR5TSHRGLA | |
| SCHEMBL17713483 | 0.76 | ADRA1D (0.40) | PLCG1 | |
| SCHEMBL1792921 | 0.76 | WDR5 (0.40) | EDNRBEDNRAWDR5TSHRGLA | |
| SCHEMBL2594694 | 0.76 | TSHR (0.37) | EDNRBEDNRAWDR5TSHRGLA | |
| SCHEMBL7376519 | 0.76 | CYP2A6 (0.39) | EDNRBEDNRAWDR5TSHRGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011123937-A1 | KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME | UNIVERSITY HEALTH NETWORK (CA) | 2011-10-13 | — | — | WO | disclosed |