SCHEMBL25564159

SCHEMBL25564159

c1ccc(-c2cccc(-c3ccccc3)c2-n2ccnc2-c2ccccc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KDR P35968 17/20 0.46
FLT1 P17948 4/20 0.42
FLT4 P35916 4/20 0.42
MAPK9 P45984 1/20 0.42
MAPK10 P53779 1/20 0.42
HSD11B1 P28845 1/20 0.41
ESR1 P03372 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3816909 0.91 TOP1 (0.42) KDRFLT1FLT4
SCHEMBL15315976 0.87 KDR (0.47) KDRFLT1FLT4MAPK9MAPK10
SCHEMBL21141830 0.87 FLT1 (0.44) KDRFLT1FLT4
SCHEMBL12797971 0.86 KDR (0.43) KDRFLT1FLT4MAPK9MAPK10
SCHEMBL15315985 0.85 KDR (0.44) KDRFLT1FLT4MAPK9MAPK10
SCHEMBL16203401 0.85 ALDH1A1 (0.45) KDRFLT1FLT4MAPK9MAPK10
SCHEMBL15316007 0.84 HTR2C (0.43) KDRFLT1FLT4MAPK9MAPK10
SCHEMBL26043894 0.83 ALDH1A1 (0.40) KDRFLT1FLT4MAPK9MAPK10
SCHEMBL20375667 0.83 CLK4 (0.47)
SCHEMBL15316045 0.83 HSD11B1 (0.39) KDRFLT1FLT4MAPK9MAPK10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230354692-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-02 US disclosed
US-11778897-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-10-03 US disclosed
US-11758804-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-09-12 US disclosed
US-11672165-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-06-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11758804-B2 Organic electroluminescent materials and devices OCIAD1, OSBP, OCIAD2 KDR 2903/4885FLT1 4002/4885FLT4 4233/4885
US-11778897-B2 Organic electroluminescent materials and devices LIFR, LBR, ZFR KDR 1211/4885FLT1 3227/4885FLT4 1927/4885
US-20230354692-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIFR, LBR, ZFR KDR 1211/4885FLT1 3227/4885FLT4 1927/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.