SCHEMBL3816909

SCHEMBL3816909

Fc1ccc(-c2nccn2-c2c(-c3ccccc3)cccc2-c2ccccc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TOP1 P11387 2/20 0.42
ALDH1A3 P47895 1/20 0.42
KDR P35968 10/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
NPSR1 Q6W5P4 1/20 0.39
AKT1 P31749 1/20 0.39
CDK1 P06493 1/20 0.39
CDK4 P11802 1/20 0.39
CCNB1 P14635 1/20 0.39
CCNA2 P20248 1/20 0.39
CCND1 P24385 1/20 0.39
CDK2 P24941 1/20 0.39
CDK7 P50613 1/20 0.39
CCNH P51946 1/20 0.39
ADORA1 P30542 1/20 0.38
KDM4E B2RXH2 1/20 0.38
FLT1 P17948 3/20 0.38
FLT4 P35916 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25564159 0.91 KDR (0.46) KDRFLT1FLT4
SCHEMBL3821581 0.89 TOP1 (0.45) TOP1ALDH1A3KDRMEN1KMT2A
SCHEMBL15315976 0.85 KDR (0.47) TOP1KDRAKT1FLT1FLT4
SCHEMBL3825222 0.83 TOP1 (0.39) TOP1KDRFLT1FLT4
SCHEMBL12797946 0.82 BACE1 (0.39) TOP1KDRNPSR1FLT1FLT4
SCHEMBL5576443 0.82 TOP1 (0.38) TOP1KDRFLT1FLT4
Biphenyl SCHEMBL28821795 0.80 MAPK9 (0.46) TOP1KDRMEN1KMT2ACDK1
SCHEMBL3827208 0.80 KDM4E (0.42) KDRMEN1KMT2ANPSR1KDM4E
SCHEMBL2049367 0.80 MAPK9 (0.48) KDRMEN1KMT2ACDK1CDK4
SCHEMBL10035798 0.80 MAPK9 (0.51) KDRMEN1KMT2AFLT1FLT4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250127030-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2025-04-17 US disclosed
US-12171138-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-12-17 US disclosed
US-20220328774-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-10-13 US disclosed
CN-115160374-A Stable OLED materials and devices with improved stability 通用显示公司 2022-10-11 CN disclosed
US-11404650-B2 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-08-02 US disclosed
US-10381579-B2 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-08-13 US disclosed
CN-107011388-A Stability OLED materials and the device with improved stability 通用显示公司 2017-08-04 CN disclosed
US-20150249225-A1 STABILITY OLED MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-09-03 US disclosed
US-9051344-B2 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2015-06-09 US disclosed
US-7902374-B2 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2011-03-08 US disclosed
EP-1878053-B1 STABILITY OLED MATERIALS AND DEVICES WITH IMPROVED STABILITY UNIVERSAL DISPLAY CORP (US) 2009-08-26 EP disclosed
WO-2008054584-A1 IMPROVED STABILITY OLED MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2008-05-08 WO disclosed
EP-1878053-A1 STABILITY OLED MATERIALS AND DEVICES WITH IMPROVED STABILITY Universal Display Corporation (US) 2008-01-16 EP disclosed
US-20070088167-A1 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION 2007-04-19 US disclosed
WO-2006121811-A1 STABILITY OLED MATERIALS AND DEVICES WITH IMPROVED STABILITY UNIVERSAL DISPLAY CORPORATION (US) 2006-11-16 WO disclosed
US-20060251923-A1 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION 2006-11-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220328774-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OSBP2, EML4, OSBP TOP1 4204/4885ALDH1A3 420/4885KDR 797/4885
US-11404650-B2 Stability OLED materials and devices OCIAD2, OCIAD1, OSBP2 TOP1 3777/4885ALDH1A3 1177/4885KDR 1067/4885
US-10381579-B2 Stability OLED materials and devices OCIAD2, OCIAD1, OSBP2 TOP1 3788/4885ALDH1A3 1190/4885KDR 1148/4885
US-20250127030-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OSBP2, EML4, OSBP TOP1 4209/4885ALDH1A3 406/4885KDR 818/4885
US-12171138-B2 Organic electroluminescent materials and devices OSBP2, EML4, OSBP TOP1 4204/4885ALDH1A3 420/4885KDR 797/4885
US-20150249225-A1 STABILITY OLED MATERIALS AND DEVICES OCIAD2, OCIAD1, OSBP2 TOP1 3788/4885ALDH1A3 1190/4885KDR 1148/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.