Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25558120 | 0.91 | HRH3 (0.39) | FAAHKCNH2HRH3L3MBTL1MEN1 | |
| SCHEMBL22520608 | 0.88 | HRH3 (0.44) | FAAHKCNH2HRH3L3MBTL1MEN1 | |
| SCHEMBL24669824 | 0.84 | CACNA2D1 (0.41) | FAAHKCNH2HRH3ALDH1A1CYP2D6 | |
| SCHEMBL25558060 | 0.84 | CHRNB2 (0.43) | KCNH2CHRNB2CHRNA3CHRNA4CHRNB3 | |
| SCHEMBL27425177 | 0.83 | CACNA2D1 (0.45) | FAAHL3MBTL1MEN1ALDH1A1KMT2A | |
| SCHEMBL25558598 | 0.82 | KCNH2 (0.38) | FAAHKCNH2HRH3HTR4CYP2D6 | |
| SCHEMBL12413703 | 0.82 | MAPT (0.48) | TP53THRBMAPT | |
| SCHEMBL25551823 | 0.80 | KCNH2 (0.40) | KCNH2HRH3HTR4CYP2D6EPHX2 | |
| SCHEMBL25560580 | 0.79 | HRH3 (0.39) | KCNH2HRH3HTR4NPSR1 | |
| SCHEMBL22520730 | 0.79 | HSD11B1 (0.41) | FAAHL3MBTL1MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023096995-A1 | COMPOSITIONS AND METHODS COMPRISING SUBSTITUTED N-(2-CHLORO-6-METHYLPHENYL)-2-((6-(6-MEMBERED HETEROCYCLOALKYL)-2-METHYLPYRIMIDIN-4-YL)AMINO)THIAZOLE-5-CARBOXAMIDE ANALOGUES | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. (US) | 2023-06-01 | — | — | WO | disclosed |