SCHEMBL25565745

SCHEMBL25565745

CCN(CCCNC(C)C)CCCOC(C)C

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 2/20 0.36
ALDH1A1 P00352 2/20 0.36
KDM4E B2RXH2 1/20 0.35
LMNA P02545 1/20 0.33
ADRB2 P07550 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25565765 0.95 ALDH1A1 (0.35) HRH3ALDH1A1KDM4ELMNA
SCHEMBL25565746 0.85 PAOX (0.36) HRH3ALDH1A1
SCHEMBL20118757 0.85 KDM4E (0.42) HRH3ALDH1A1KDM4E
SCHEMBL25565753 0.82 ALDH1A1 (0.38) HRH3ALDH1A1KDM4ELMNAADRB2
SCHEMBL25565758 0.81 KDM4E (0.41) HRH3ALDH1A1KDM4E
SCHEMBL25569452 0.81 PAOX (0.38) HRH3ALDH1A1
SCHEMBL19546118 0.81 PAOX (0.34) HRH3ALDH1A1
SCHEMBL152809 0.81 PAOX (0.40) HRH3ALDH1A1LMNA
SCHEMBL12028002 0.81 KDM4E (0.42) HRH3ALDH1A1KDM4ELMNA
SCHEMBL25565757 0.79 KDM4E (0.38) ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11859201-B2 Nanoparticle compositions containing sugar functionalized nucleic acid carriers TIBA BIOTECH LLC (US) 2024-01-02 US disclosed
US-20230149562-A1 CARRIERS FOR EFFICIENT NUCLEIC ACID DELIVERY TIBA BIOTECH LLC (US) 2023-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230149562-A1 CARRIERS FOR EFFICIENT NUCLEIC ACID DELIVERY POLN, TLR9, TSG101 HRH3 3364/4885ALDH1A1 3979/4885KDM4E 4832/4885
US-11859201-B2 Nanoparticle compositions containing sugar functionalized nucleic acid carriers TLR9, TLR3, TSG101 HRH3 4165/4885ALDH1A1 3422/4885KDM4E 4820/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.