SCHEMBL25565753

SCHEMBL25565753

CC(C)NCCCN(C)CCCOC(C)C

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.38
LMNA P02545 1/20 0.32
ADRB2 P07550 1/20 0.32
TP53 P04637 1/20 0.31
PKM P14618 1/20 0.31
HRH3 Q9Y5N1 1/20 0.31
KDM4E B2RXH2 1/20 0.31
HTR1B P28222 1/20 0.31
NR2E1 Q9Y466 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25075500 0.95 ALDH1A1 (0.37) ALDH1A1LMNAADRB2TP53PKM
SCHEMBL25569663 0.91 ALDH1A1 (0.37) ALDH1A1LMNAADRB2TP53PKM
SCHEMBL25565751 0.84 KDM4E (0.38) ALDH1A1TP53PKMKDM4ESMN1; SMN2
SCHEMBL12542134 0.84 MAPT (0.35) LMNAADRB2TP53HRH3HTR1B
SCHEMBL19502501 0.83 SIGMAR1 (0.38) ALDH1A1TP53PKMKDM4ESMN1; SMN2
SCHEMBL25565745 0.82 HRH3 (0.36) ALDH1A1LMNAADRB2HRH3KDM4E
SCHEMBL12703408 0.82 ALDH1A1 (0.50) ALDH1A1LMNAADRB2HTR1BNR2E1
SCHEMBL25101936 0.81 SIGMAR1 (0.39) ALDH1A1
SCHEMBL25565770 0.80 CHRM2 (0.37) ALDH1A1KDM4E
SCHEMBL24477365 0.80 ALDH1A1 (0.44) ALDH1A1LMNAADRB2HRH3KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11859201-B2 Nanoparticle compositions containing sugar functionalized nucleic acid carriers TIBA BIOTECH LLC (US) 2024-01-02 US disclosed
US-20230149562-A1 CARRIERS FOR EFFICIENT NUCLEIC ACID DELIVERY TIBA BIOTECH LLC (US) 2023-05-18 US disclosed
US-20230149562-A1 CARRIERS FOR EFFICIENT NUCLEIC ACID DELIVERY TIBA BIOTECH LLC (US) 2023-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230149562-A1 CARRIERS FOR EFFICIENT NUCLEIC ACID DELIVERY POLN, TLR9, TSG101 ALDH1A1 3979/4885LMNA 72/4885ADRB2 4665/4885
US-11859201-B2 Nanoparticle compositions containing sugar functionalized nucleic acid carriers TLR9, TLR3, TSG101 ALDH1A1 3422/4885LMNA 449/4885ADRB2 4843/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.