Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 5/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22859167 | 1.00 | NCF1 (0.54) | NCF1ACHECYP2D6CYP1A2HRH3 | |
| SCHEMBL25566048 | 1.00 | NCF1 (0.54) | NCF1ACHECYP2D6CYP1A2HRH3 | |
| SCHEMBL12371223 | 0.95 | NCF1 (0.52) | NCF1ACHECYP2D6CYP1A2HRH3 | |
| SCHEMBL27267695 | 0.92 | NCF1 (0.52) | NCF1ACHECYP2D6CYP1A2HRH3 | |
| SCHEMBL757866 | 0.92 | NCF1 (0.62) | NCF1ACHECYP2D6CYP1A2HRH3 | |
| SCHEMBL18636207 | 0.91 | NCF1 (0.46) | NCF1ACHECYP2D6CYP1A2HRH3 | |
| SCHEMBL19892365 | 0.88 | NCF1 (0.43) | NCF1ACHECYP2D6CYP1A2HRH3 | |
| SCHEMBL25565872 | 0.84 | GNAO1 (0.41) | NCF1ACHECYP2D6CYP1A2HRH3 | |
| SCHEMBL27269253 | 0.83 | NCF1 (0.43) | NCF1ACHEHRH3HRH4CHRM3 | |
| SCHEMBL8363126 | 0.82 | NCF1 (0.52) | NCF1ACHECYP1A2HRH3HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023083194-A1 | WEE1 PROTEIN KINASE DEGRADATION AGENT AND USE THEREOF | 杭州格博生物医药有限公司 | 2023-05-19 | — | — | WO | disclosed |